Homo sapiens (human): 2492
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Entry
2492 CDS
T01001
Symbol
FSHR, FSHR1, FSHRO, LGR1, ODG1
Name
(RefSeq) follicle stimulating hormone receptor
KO
K04247
follicle stimulating hormone receptor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04024
cAMP signaling pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04913
Ovarian steroidogenesis
Network
nt06323
KISS1-GnRH-LH/FSH-E2 signaling
Element
N00922
FSHR-GNAS-PKA signaling pathway
Disease
H00599
Ovarian dysgenesis
H01039
Ovarian hyperstimulation syndrome
Drug target
Chorionic gonadotrophin:
D06457
<JP/US>
Corifollitropin alfa:
D08895
Cyclofenil:
D01281
<JP>
Follitropin alfa:
D04429
<JP/US>
Follitropin beta:
D04430
<JP/US>
Follitropin delta:
D06400
<JP>
Human menopausal gonadotrophin (
DG00472
):
D02692
<JP>
D06459
<JP>
Serum gonadotrophin:
D05258
Urofollitropin:
D06269
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
2492 (FSHR)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
2492 (FSHR)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
2492 (FSHR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
2492 (FSHR)
G protein-coupled receptors [BR:
hsa04030
]
Rhodopsin family
Peptide
Follicle stimulating hormone (FSH)
2492 (FSHR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_1
GnHR_trans
LRR_8
LRR_5
LRR_4
LRRNT
LRR_9
Motif
Other DBs
NCBI-GeneID:
2492
NCBI-ProteinID:
NP_000136
OMIM:
136435
HGNC:
3969
Ensembl:
ENSG00000170820
Pharos:
P23945
(Tclin)
UniProt:
P23945
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(48962157..49154515)
Genome browser
AA seq
695 aa
AA seq
DB search
MALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRV
IQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
NLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKN
GIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLEN
LKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQE
VDYMTQARGQRSSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIM
GYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIAS
VDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCK
VQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVL
AFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVP
LITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSS
TVHNTHPRNGHCSSAPRVTSGSTYILVPLSHLAQN
NT seq
2088 nt
NT seq
+upstream
nt +downstream
nt
atggccctgctcctggtctctttgctggcattcctgagcttgggctcaggatgtcatcat
cggatctgtcactgctctaacagggtttttctctgccaagagagcaaggtgacagagatt
ccttctgacctcccgaggaatgccattgaactgaggtttgtcctcaccaagcttcgagtc
atccaaaaaggtgcattttcaggatttggggacctggagaaaatagagatctctcagaat
gatgtcttggaggtgatagaggcagatgtgttctccaaccttcccaaattacatgaaatt
agaattgaaaaggccaacaacctgctctacatcaaccctgaggccttccagaaccttccc
aaccttcaatatctgttaatatccaacacaggtattaagcaccttccagatgttcacaag
attcattctctccaaaaagttttacttgacattcaagataacataaacatccacacaatt
gaaagaaattctttcgtggggctgagctttgaaagtgtgattctatggctgaataagaat
gggattcaagaaatacacaactgtgcattcaatggaacccaactagatgagctgaatcta
agcgataataataatttagaagaattgcctaatgatgttttccacggagcctctggacca
gtcattctagatatttcaagaacaaggatccattccctgcctagctatggcttagaaaat
cttaagaagctgagggccaggtcgacttacaacttaaaaaagctgcctactctggaaaag
cttgtcgccctcatggaagccagcctcacctatcccagccattgctgtgcctttgcaaac
tggagacggcaaatctctgagcttcatccaatttgcaacaaatctattttaaggcaagaa
gttgattatatgactcaggctaggggtcagagatcctctctggcagaagacaatgagtcc
agctacagcagaggatttgacatgacgtacactgagtttgactatgacttatgcaatgaa
gtggttgacgtgacctgctcccctaagccagatgcattcaacccatgtgaagatatcatg
gggtacaacatcctcagagtcctgatatggtttatcagcatcctggccatcactgggaac
atcatagtgctagtgatcctaactaccagccaatataaactcacagtccccaggttcctt
atgtgcaacctggcctttgctgatctctgcattggaatctacctgctgctcattgcatca
gttgatatccataccaagagccaatatcacaactatgccattgactggcaaactggggca
ggctgtgatgctgctggctttttcactgtctttgccagtgagctgtcagtctacactctg
acagctatcaccttggaaagatggcataccatcacgcatgccatgcagctggactgcaag
gtgcagctccgccatgctgccagtgtcatggtgatgggctggatttttgcttttgcagct
gccctctttcccatctttggcatcagcagctacatgaaggtgagcatctgcctgcccatg
gatattgacagccctttgtcacagctgtatgtcatgtccctccttgtgctcaatgtcctg
gcctttgtggtcatctgtggctgctatatccacatctacctcacagtgcggaaccccaac
atcgtgtcctcctctagtgacaccaggatcgccaagcgcatggccatgctcatcttcact
gacttcctctgcatggcacccatttctttctttgccatttctgcctccctcaaggtgccc
ctcatcactgtgtccaaagcaaagattctgctggttctgtttcaccccatcaactcctgt
gccaaccccttcctctatgccatctttaccaaaaactttcgcagagatttcttcattctg
ctgagcaagtgtggctgctatgaaatgcaagcccaaatttataggacagaaacttcatcc
actgtccacaacacccatccaaggaatggccactgctcttcagctcccagagtcaccagt
ggttccacttacatacttgtccctctaagtcatttagcccaaaactaa
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