| Entry |
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| Name |
Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
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| Definition |
NleE -| (TAB2/3) |
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| Expanded |
K23654 -| (23118,257397) |
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| Class |
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| Type |
Pathogen
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| Pathway |
| hsa05130 | Pathogenic Escherichia coli infection |
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| Disease |
| H00277 | Enterohemorrhagic Escherichia coli (EHEC) infection |
| H00278 | Enteropathogenic Escherichia coli (EPEC) infection |
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| Gene |
| 23118 | TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2 |
| 257397 | TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3 |
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| Perturbant |
| K23654 (NleE) | nleE; T3SS secreted effector NleE |
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| Reference |
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| Authors |
Zhang L, Ding X, Cui J, Xu H, Chen J, Gong YN, Hu L, Zhou Y, Ge J, Lu Q, Liu L, Chen S, Shao F |
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| Title |
Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation. |
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| Journal |
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| Reference |
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| Authors |
Ruchaud-Sparagano MH, Muhlen S, Dean P, Kenny B |
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| Title |
The enteropathogenic E. coli (EPEC) Tir effector inhibits NF-kappaB activity by targeting TNFalpha receptor-associated factors. |
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| Journal |
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| Reference |
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| Authors |
Zhang Y, Muhlen S, Oates CV, Pearson JS, Hartland EL |
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| Title |
Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ. |
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| Journal |
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| LinkDB |
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