KEGG   ORTHOLOGY: K23654
Entry
K23654                      KO                                     
Symbol
nleE, ospZ
Name
T3SS secreted effector NleE
Pathway
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
Network
nt06123  TNF signaling (viruses and bacteria)
  Element
N00927  Escherichia/Shigella NleE/OspZ to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K23654  nleE, ospZ; T3SS secreted effector NleE
   05131 Shigellosis
    K23654  nleE, ospZ; T3SS secreted effector NleE
Genes
ECE: Z4329
ECS: ECs_3858(nleE)
ECF: ECH74115_4287
ETW: ECSP_3954(nleE)
ELX: CDCO157_3605
EOI: ECO111_3726 ECO111_5004
EOJ: ECO26_5293
EOH: ECO103_3562(nleE) ECO103_4916(nleE)
ECOO: ECRM13514_5385(nleE)
ECOH: ECRM13516_5228(nleE)
EOK: G2583_3639(nleE)
SFE: SFxv_5129
SSN: SSON_P240
SBO: SBO_P147
SDY: SDY_P221
CRO: ROD_10841(nleE)
 » show all
Reference
  Authors
Newton HJ, Pearson JS, Badea L, Kelly M, Lucas M, Holloway G, Wagstaff KM, Dunstone MA, Sloan J, Whisstock JC, Kaper JB, Robins-Browne RM, Jans DA, Frankel G, Phillips AD, Coulson BS, Hartland EL
  Title
The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.
  Journal
PLoS Pathog 6:e1000898 (2010)
DOI:10.1371/journal.ppat.1000898
  Sequence
[ece:Z4329] [sdy:SDY_P221]
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