KEGG   NETWORK: N00988
Entry
N00988                      Network                                
Name
Electron transfer in Complex II
Definition
Succinate -- CxII -> QH2
  Expanded
C00042 -- (6389+6390+6391+6392) -> C00390
Class
nt06252 Mitochondrial ROS formation (cancer)
nt06460 Alzheimer disease
nt06463 Parkinson disease
nt06461 Huntington disease
nt06466 Pathways of neurodegeneration
Type
Reference
Pathway
hsa00190  Oxidative phosphorylation
Gene
6389  SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390  SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391  SDHC; succinate dehydrogenase complex subunit C
6392  SDHD; succinate dehydrogenase complex subunit D
Metabolite
C00042  Succinate
C00390  Ubiquinol
Reference
PMID:29225013
  Authors
Jodeiri Farshbaf M, Kiani-Esfahani A
  Title
Succinate dehydrogenase: Prospect for neurodegenerative diseases.
  Journal
Mitochondrion 42:77-83 (2018)
DOI:10.1016/j.mito.2017.12.002
Reference
PMID:10066163
  Authors
Saraste M
  Title
Oxidative phosphorylation at the fin de siecle.
  Journal
Science 283:1488-93 (1999)
DOI:10.1126/science.283.5407.1488
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