| Entry |
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| Name |
Shigella IpaB/C/D to ITGA/B-TALIN/VINCULIN signaling pathway
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| Definition |
(IpaB+IpaC,IpaD) -> (ITGA5+ITGB1) -> (PTK2+PXN) -> (TLN+VCN) -> (ACTB,ACTG1) |
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| Expanded |
((K13285+K13286),K13287) -> (3678+3688) -> (5747+5829) -> ((7094,83660)+7414) -> (60,71) |
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| Class |
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| Type |
Pathogen
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| Pathway |
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| Disease |
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| Gene |
| 3678 | ITGA5; integrin subunit alpha 5 |
| 3688 | ITGB1; integrin subunit beta 1 |
| 5747 | PTK2; protein tyrosine kinase 2 |
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| Perturbant |
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| Reference |
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| Authors |
Watarai M, Kamata Y, Kozaki S, Sasakawa C |
|---|
| Title |
rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells. |
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| Journal |
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| Reference |
|
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| Authors |
Watarai M, Funato S, Sasakawa C |
|---|
| Title |
Interaction of Ipa proteins of Shigella flexneri with alpha5beta1 integrin promotes entry of the bacteria into mammalian cells. |
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| Journal |
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| LinkDB |
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