KEGG   NETWORK: N01124
Entry
N01124                      Network                                
Name
Salmonella AvrA to beta-catenin signaling pathway
Definition
AvrA -> CTNNB1 -> TCF/LEF => MYC
  Expanded
K08598 -> 1499 -> (6932,83439,6934,51176) => 4609
Class
nt06505 WNT signaling
nt06181 Salmonella
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
1499  CTNNB1; catenin beta 1
6932  TCF7; transcription factor 7
83439  TCF7L1; transcription factor 7 like 1
6934  TCF7L2; transcription factor 7 like 2
51176  LEF1; lymphoid enhancer binding factor 1
4609  MYC; MYC proto-oncogene, bHLH transcription factor
Perturbant
K08598 (AvrA)  yopJ; YopJ protease family
Reference
PMID:17690189
  Authors
Ye Z, Petrof EO, Boone D, Claud EC, Sun J
  Title
Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination.
  Journal
Am J Pathol 171:882-92 (2007)
DOI:10.2353/ajpath.2007.070220
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