KEGG   NETWORK: N01305
Entry
N01305                      Network                                
Name
Salmonella SopB to ANXA2-S100A10-regulated actin cytoskeleton
Definition
(SopB,SopE) -> (ANXA2+S100A10) -- AHNAK -- (ACTB,ACTG1)
  Expanded
(K13085,K13741) -> (302+6281) -- 79026 -- (60,71)
Class
nt06135 Cytoskeletal regulation (viruses and bacteria)
Type
Pathogen
Pathway
hsa05132  Salmonella infection
Disease
H00113  Salmonellosis
Gene
302  ANXA2; annexin A2
6281  S100A10; S100 calcium binding protein A10
79026  AHNAK; AHNAK nucleoprotein
60  ACTB; actin beta
71  ACTG1; actin gamma 1
Perturbant
K13085 (SopB)  ipgD; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
K13741 (SopE)  sopE; guanine nucleotide exchange factor SopE
Reference
  Authors
Jolly C, Winfree S, Hansen B, Steele-Mortimer O
  Title
The Annexin A2/p11 complex is required for efficient invasion of Salmonella Typhimurium in epithelial cells.
  Journal
Cell Microbiol 16:64-77 (2014)
DOI:10.1111/cmi.12180
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