| Entry |
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| Symbol |
ipgD, sopB
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| Name |
phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC: 3.1.3.78]
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| Pathway |
| map05100 | Bacterial invasion of epithelial cells |
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| Reaction |
| R08981 | 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase |
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| Network |
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| Element |
| N01067 | Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway |
| N01129 | Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway |
| N01130 | Salmonella SopB to RhoA signaling pathway |
| N01133 | Salmonella SopB to RhoG signaling pathway |
| N01134 | Salmonella SopB to CDC42 signaling pathway |
| N01303 | Salmonella SopB to Early endosomal fusion |
| N01305 | Salmonella SopB to ANXA2-S100A10-regulated actin cytoskeleton |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
05131 Shigellosis
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
05100 Bacterial invasion of epithelial cells
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
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| Genes |
» show all
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| Reference |
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| Authors |
Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B |
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| Title |
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology. |
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| Journal |
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| Sequence |
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| LinkDB |
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