KEGG   ORTHOLOGY: K13085
Entry
K13085                      KO                                     
Symbol
ipgD, sopB
Name
phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
Pathway
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05132  Salmonella infection
Network
nt06125  Membrane trafficking (bacteria)
nt06135  Cytoskeletal regulation (viruses and bacteria)
nt06526  MAPK signaling
  Element
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
N01133  Salmonella SopB to RhoG signaling pathway
N01134  Salmonella SopB to CDC42 signaling pathway
N01303  Salmonella SopB to Early endosomal fusion
N01305  Salmonella SopB to ANXA2-S100A10-regulated actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
   05131 Shigellosis
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
   05100 Bacterial invasion of epithelial cells
    K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.78  phosphatidylinositol-4,5-bisphosphate 4-phosphatase
     K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase
Other DBs
RN: R08981
Genes
EMA: C1192_24285
STY: STY1121(sigD)
STT: t1828(sigD)
SEX: STBHUCCB_19440
SENT: TY21A_09295
STM: STM1091(sopB)
SEO: STM14_1237(sopB)
SEV: STMMW_11031
SEY: SL1344_1030(sopB)
SEM: STMDT12_C11120
SEJ: STMUK_1060(sopB)
SEB: STM474_1083(sopB)
SEF: UMN798_1133(sigD)
SETU: STU288_01790
SETC: CFSAN001921_11720(sopB)
SENR: STMDT2_10271(sigD)
SEND: DT104_10731(sopB)
SENI: CY43_05575(sopB)
SEEN: SE451236_11305(sopB)
SPT: SPA1759(sigD)
SEK: SSPA1634
SPQ: SPAB_02464
SEI: SPC_2659(sigD)
SEC: SCH_1043(sopB)
SEH: SeHA_C1201
SHB: SU5_01724
SENH: CFSAN002069_03565(sopB)
SEEH: SEEH1578_14685
SEE: SNSL254_A1187
SENN: SN31241_21590
SEW: SeSA_A1155
SEA: SeAg_B1050
SENS: Q786_04870(sopB)
SED: SeD_A1167
SEG: SG0980(sopB)
SEL: SPUL_1966(sopB)
SEGA: SPUCDC_1952(sopB)
SET: SEN0955(sopB)
SENA: AU38_04930(sopB)
SENO: AU37_04920(sopB)
SENV: AU39_04920(sopB)
SENQ: AU40_05535(sopB)
SENL: IY59_05020(sopB)
SENJ: CFSAN001992_06185
SEEC: CFSAN002050_11850(sopB)
SEEB: SEEB0189_014115(sopB)
SEEP: I137_08940(sopB)
SENB: BN855_10450
SENE: IA1_05370(sopB)
SENC: SEET0819_12115(sopB)
SES: SARI_01910
SBG: SBG_0939(sopB)
SBZ: A464_1030
SBV: N643_04465(sopB)
SALZ: EOS98_14165
SFL: CP0133(ipgD)
SFE: SFxv_4976(ipgD)
SSN: SSON_P095(ipgD)
SBC: SbBS512_A0166(ipgD)
SDY: SDY_P171(ipgD)
SDZ: Asd1617_06366
SYM: K6K13_10905
YAL: AT01_2850(sopB)
FSM: CCS41_07775
RBAD: H2866_19305
SOD: Sant_3206(sigD) Sant_3209(sigD2)
SLIG: GTU79_05195
PAY: PAU_01919
PSI: S70_12925
PSX: DR96_586(sopB)
PSTA: BGK56_15810
PVC: G3341_17095
PTHA: OI982_10265
ANS: ArsFIN_43100(sopB)
VAN: VAA_02157
LAG: N175_09340
VAU: VANGNB10_cI1105
CRZ: D1345_19490
CHAE: CH06BL_40220(sopB_sigD)
IFL: C1H71_17665(sopB)
PPK: U875_18870
PPNO: DA70_11385
PPNM: LV28_19660
LIMN: HKT17_05800
BGM: CAL15_03515
CDN: BN940_04026
PVAC: HC248_01669(ipgD)
COF: FOZ74_09105
STAR: G3545_19400
HMC: HYPMC_3453
PSF: PSE_2750(ipgD)
DPG: DESPIGER_2147
OXY: HCG48_18215
PCU: PC_RS06055
PNL: PNK_0614(ipgD)
 » show all
Reference
PMID:12356723
  Authors
Niebuhr K, Giuriato S, Pedron T, Philpott DJ, Gaits F, Sable J, Sheetz MP, Parsot C, Sansonetti PJ, Payrastre B
  Title
Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology.
  Journal
EMBO J 21:5069-78 (2002)
DOI:10.1093/emboj/cdf522
  Sequence
[sfl:CP0133]
LinkDB

DBGET integrated database retrieval system