Entry |
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Name |
Manganese to electron transfer in Complex II
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Definition |
Mn2+ -| CxII -> QH2 |
Expanded |
C19610 -| (6389+6390+6391+6392) -> C00390 |
Class |
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Type |
Env factor
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Pathway |
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Disease |
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Gene |
6389 | SDHA; succinate dehydrogenase complex flavoprotein subunit A |
6390 | SDHB; succinate dehydrogenase complex iron sulfur subunit B |
6391 | SDHC; succinate dehydrogenase complex subunit C |
6392 | SDHD; succinate dehydrogenase complex subunit D |
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Perturbant |
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Metabolite |
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Reference |
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Authors |
Martins AC Jr, Morcillo P, Ijomone OM, Venkataramani V, Harrison FE, Lee E, Bowman AB, Aschner M |
Title |
New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease. |
Journal |
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Reference |
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Authors |
Gunter TE, Gerstner B, Lester T, Wojtovich AP, Malecki J, Swarts SG, Brookes PS, Gavin CE, Gunter KK |
Title |
An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays. |
Journal |
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Reference |
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Authors |
Bonke E, Zwicker K, Drose S |
Title |
Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II. |
Journal |
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LinkDB |
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