| Entry |
|
| Name |
Manganese to electron transfer in Complex II
|
| Definition |
Mn2+ -| CxII -> QH2 |
| Expanded |
C19610 -| (6389+6390+6391+6392) -> C00390 |
| Class |
|
| Type |
Env factor
|
| Pathway |
|
| Disease |
|
| Gene |
| 6389 | SDHA; succinate dehydrogenase complex flavoprotein subunit A |
| 6390 | SDHB; succinate dehydrogenase complex iron sulfur subunit B |
| 6391 | SDHC; succinate dehydrogenase complex subunit C |
| 6392 | SDHD; succinate dehydrogenase complex subunit D |
|
| Perturbant |
|
| Metabolite |
|
| Reference |
|
| Authors |
Martins AC Jr, Morcillo P, Ijomone OM, Venkataramani V, Harrison FE, Lee E, Bowman AB, Aschner M |
| Title |
New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease. |
| Journal |
|
| Reference |
|
| Authors |
Gunter TE, Gerstner B, Lester T, Wojtovich AP, Malecki J, Swarts SG, Brookes PS, Gavin CE, Gunter KK |
| Title |
An analysis of the effects of Mn2+ on oxidative phosphorylation in liver, brain, and heart mitochondria using state 3 oxidation rate assays. |
| Journal |
|
| Reference |
|
| Authors |
Bonke E, Zwicker K, Drose S |
| Title |
Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II. |
| Journal |
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| LinkDB |
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