| Entry |
|
|---|
| Symbol |
WNT5A, hWNT5A
|
|---|
| Name |
(RefSeq) Wnt family member 5A
|
|---|
| KO |
| K00444 | wingless-type MMTV integration site family, member 5 |
|
|---|
| Organism |
|
|---|
| Pathway |
| hsa04550 | Signaling pathways regulating pluripotency of stem cells |
| hsa05022 | Pathways of neurodegeneration - multiple diseases |
|
|---|
| Network |
|
|---|
| Element |
| N00010 | Mutation-inactivated PTCH1 to Hedgehog signaling pathway |
| N00017 | Mutation-activated SMO to Hedgehog signaling pathway |
| N00059 | FZD7-overexpression to Wnt signaling pathway |
| N00060 | LRP6-overexpression to Wnt signaling pathway |
| N01427 | WNT5A-ROR signaling pathway |
| N01442 | Wnt signaling modulation, Wnt inhibitor |
| N01443 | Wnt signaling modulation, Wnt acylation |
|
|---|
| Disease |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
7474 (WNT5A)
04390 Hippo signaling pathway
7474 (WNT5A)
04150 mTOR signaling pathway
7474 (WNT5A)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
7474 (WNT5A)
09150 Organismal Systems
09152 Endocrine system
04916 Melanogenesis
7474 (WNT5A)
09158 Development and regeneration
04360 Axon guidance
7474 (WNT5A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7474 (WNT5A)
05205 Proteoglycans in cancer
7474 (WNT5A)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
7474 (WNT5A)
05226 Gastric cancer
7474 (WNT5A)
05217 Basal cell carcinoma
7474 (WNT5A)
05224 Breast cancer
7474 (WNT5A)
09172 Infectious disease: viral
05165 Human papillomavirus infection
7474 (WNT5A)
09164 Neurodegenerative disease
05010 Alzheimer disease
7474 (WNT5A)
05022 Pathways of neurodegeneration - multiple diseases
7474 (WNT5A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
7474 (WNT5A)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:hsa00536]
7474 (WNT5A)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
Morphogens
7474 (WNT5A)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
3:complement(55465715..55505263)
|
|---|
| AA seq |
380 aa
MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFSFAQVVIEANSWWSLGMNNPVQMSEV
YIIGAQPLCSQLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNCSTVDN
TSVFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPKDLPRDWLWG
GCGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKC
HGVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKLVQVNSRFNSPTTQDLV
YIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKFH
WCCYVKCKKCTEIVDQFVCK |
|---|
| NT seq |
1143 nt +upstreamnt +downstreamnt
atgaagaagtccattggaatattaagcccaggagttgctttggggatggctggaagtgca
atgtcttccaagttcttcctagtggctttggccatatttttctccttcgcccaggttgta
attgaagccaattcttggtggtcgctaggtatgaataaccctgttcagatgtcagaagta
tatattataggagcacagcctctctgcagccaactggcaggactttctcaaggacagaag
aaactgtgccacttgtatcaggaccacatgcagtacatcggagaaggcgcgaagacaggc
atcaaagaatgccagtatcaattccgacatcgaaggtggaactgcagcactgtggataac
acctctgtttttggcagggtgatgcagataggcagccgcgagacggccttcacatacgcg
gtgagcgcagcaggggtggtgaacgccatgagccgggcgtgccgcgagggcgagctgtcc
acctgcggctgcagccgcgccgcgcgccccaaggacctgccgcgggactggctctggggc
ggctgcggcgacaacatcgactatggctaccgctttgccaaggagttcgtggacgcccgc
gagcgggagcgcatccacgccaagggctcctacgagagtgctcgcatcctcatgaacctg
cacaacaacgaggccggccgcaggacggtgtacaacctggctgatgtggcctgcaagtgc
catggggtgtccggctcatgtagcctgaagacatgctggctgcagctggcagacttccgc
aaggtgggtgatgccctgaaggagaagtacgacagcgcggcggccatgcggctcaacagc
cggggcaagttggtacaggtcaacagccgcttcaactcgcccaccacacaagacctggtc
tacatcgaccccagccctgactactgcgtgcgcaatgagagcaccggctcgctgggcacg
cagggccgcctgtgcaacaagacgtcggagggcatggatggctgcgagctcatgtgctgc
ggccgtggctacgaccagttcaagaccgtgcagacggagcgctgccactgcaagttccac
tggtgctgctacgtcaagtgcaagaagtgcacggagatcgtggaccagtttgtgtgcaag
tag |
|---|
