KEGG   NETWORK: N01484
Entry
N01484                      Network                                
Name
Establishment of cohesion
Definition
STAG1,STAG2 == PDS5+WAPL -> CDCA5,CTCF == STAG+PDS5+WAPL
  Expanded
10274,10735 == 23244,23047+23063 -> 113130,10664 == 10274,10735+23244,23047+23063
Class
nt06512 Chromosome cohesion and segregation
Type
Reference
Gene
10274  STAG1; stromal antigen 1
10735  STAG2; stromal antigen 2
23244  PDS5A; PDS5 cohesin associated factor A
23047  PDS5B; PDS5 cohesin associated factor B
23063  WAPL; WAPL cohesin release factor
113130  CDCA5; cell division cycle associated 5
10664  CTCF; CCCTC-binding factor
Reference
  Authors
Boavida A, Santos D, Mahtab M, Pisani FM
  Title
Functional Coupling between DNA Replication and Sister Chromatid Cohesion Establishment.
  Journal
Int J Mol Sci 22:2810 (2021)
DOI:10.3390/ijms22062810
Reference
  Authors
Zhang N, Coutinho LE, Pati D
  Title
PDS5A and PDS5B in Cohesin Function and Human Disease.
  Journal
Int J Mol Sci 22:5868 (2021)
DOI:10.3390/ijms22115868
Reference
  Authors
Ouyang Z, Zheng G, Tomchick DR, Luo X, Yu H
  Title
Structural Basis and IP6 Requirement for Pds5-Dependent Cohesin Dynamics.
  Journal
Mol Cell 62:248-259 (2016)
DOI:10.1016/j.molcel.2016.02.033
Reference
  Authors
Wutz G, Ladurner R, St Hilaire BG, Stocsits RR, Nagasaka K, Pignard B, Sanborn A, Tang W, Varnai C, Ivanov MP, Schoenfelder S, van der Lelij P, Huang X, Durnberger G, Roitinger E, Mechtler K, Davidson IF, Fraser P, Lieberman-Aiden E, Peters JM
  Title
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL.
  Journal
Elife 9:e52091 (2020)
DOI:10.7554/eLife.52091
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