KEGG   Homo sapiens (human): 10735
Entry
10735             CDS       T01001                                 
Symbol
STAG2, HPE13, MKMS, NEDXCF, SA-2, SA2, SCC3B, bA517O1.1
Name
(RefSeq) STAG2 cohesin complex component
  KO
K06671  cohesin complex subunit SA-1/2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06512  Chromosome cohesion and segregation
  Element
N01482  Cohesin loading
N01484  Establishment of cohesion
N01485  Cohesin dissociation in prophase
Disease
H00267  Holoprosencephaly
H02582  Mullegama-Klein-Martinez syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    10735 (STAG2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10735 (STAG2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   Cohesin complex
    10735 (STAG2)
SSDB
Motif
Pfam: STAG SCD Cnd3 AdoHcyase_NAD
Other DBs
NCBI-GeneID: 10735
NCBI-ProteinID: NP_001036216
OMIM: 300826
HGNC: 11355
Ensembl: ENSG00000101972
Pharos: Q8N3U4(Tbio)
UniProt: Q8N3U4 Q6MZM3
Structure
LinkDB
Position
X:123960560..124102656
AA seq 1231 aa
MIAAPEIPTDFNLLQESETHFSSDTDFEDIEGKNQKQGKGKTCKKGKKGPAEKGKGGNGG
GKPPSGPNRMNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINF
FIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIG
VLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIN
MDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDA
IAEIRAICIEEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKEL
NSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSA
HRPVAVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYL
VDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVG
RGTGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIY
TTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDE
LADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGI
ENGDMPEQIVIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVN
TTVKEQAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD
NNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDII
KETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFG
LDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYV
YLEKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTG
KRKVVEGMQLSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMS
VYPMQTEHHQTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPP
SKNRRERTELKPDFFDPASIMDESVLGVSMF
NT seq 3696 nt   +upstreamnt  +downstreamnt
atgatagcagctccagaaataccaactgattttaatctactacaggagtcagaaacacat
ttttcttctgacacagattttgaagatatcgaaggaaaaaaccaaaagcaaggcaaaggc
aaaacttgtaaaaaaggcaaaaagggcccagcagaaaagggcaaaggtggaaatggagga
ggaaaacctccttctggtccaaaccgaatgaatggtcatcaccaacagaatggagtggaa
aacatgatgttgtttgaagttgttaaaatgggcaagagtgctatgcagtcggtggtagat
gattggatagaatcatacaagcatgaccgagatatagcacttcttgaccttatcaacttt
tttattcagtgttcaggctgtaaaggagttgtcacagcagaaatgtttagacatatgcag
aactctgagataattcgaaaaatgactgaagaattcgatgaggatagtggagattatcca
cttaccatggctggtcctcagtggaagaagttcaaatccagtttttgtgaattcattggc
gtgttagtacggcaatgtcaatatagtatcatatatgatgagtatatgatggatacagtc
atttcacttcttacaggattgtctgactcacaagtcagagcatttcgacatacaagcacc
ctggcagctatgaagttgatgacagctttggtgaatgtggcactaaatcttagcattaat
atggataatacacaaagacaatatgaagcagaacggaataaaatgattggaaaacgagcc
aatgagaggctagaactcctgctacaaaagcggaaagagcttcaggaaaatcaagatgaa
atagaaaatatgatgaatgcaatatttaaaggagtgtttgtacatagataccgtgatgcg
atagctgaaattcgagctatttgcattgaagagattggcatttggatgaagatgtatagt
gatgcctttcttaatgacagttatttaaaatatgttggttggactatgcatgataagcaa
ggtgaagtaagactcaaatgtcttactgctctacaagggctttattataacaaagagctt
aattccaaactggaactttttaccagtcggttcaaggatagaattgtgtctatgaccctt
gacaaagaatatgatgttgcagtacaagcaataaaattactcactcttgttttacagagt
agtgaagaagttctcactgcagaagattgtgaaaatgtctatcatctggtttattcagct
caccggccagtagcagtagcagctggagaatttctctacaaaaagctcttcagtcgtaga
gatccagaggaggatggaatgatgaaaagaagaggaagacaaggtccaaatgccaacctt
gttaagacattggtttttttctttctagaaagtgagttacatgagcatgcagcatacctt
gtggatagcatgtgggactgtgctactgagctgctgaaagactgggaatgtatgaatagc
ttgttactggaagagccacttagtggagaggaagcactaacagataggcaagagagtgct
ctgattgaaataatgctttgtaccattagacaagcggctgaatgtcatcctcccgtggga
agagggacaggaaaaagggtgcttacagcaaaggagaagaagacacagttggatgatagg
acaaaaatcactgagctttttgccgtggcccttcctcagttattagcaaaatactctgta
gatgcagaaaaggtgactaacttgttgcagttgcctcagtactttgatttggaaatatat
accactggacgattagaaaagcatttggatgccttattgcgacagatccggaatattgta
gagaagcacacagatacagatgttttggaagcatgttctaaaacttaccatgcactctgt
aatgaagagttcacaatcttcaacagagtagatatttcaagaagtcaactgatagatgaa
ttggcagataaatttaaccggcttcttgaagattttctgcaagagggtgaagaacctgat
gaagatgatgcatatcaggtattgtcaacattgaagaggatcactgcttttcataatgcc
catgacctttcaaagtgggatttatttgcttgtaattacaaactcttgaaaactggaatc
gaaaatggagacatgcctgagcagattgttattcacgcactgcagtgtactcactatgta
atcctttggcaacttgctaagataactgaaagcagctctacaaaggaggacttgctgcgt
ttaaagaaacaaatgagagtattttgtcagatatgtcaacattacctgaccaacgtgaat
actactgttaaggaacaggccttcactattctgtgtgatattttgatgatcttcagccat
cagattatgtcaggagggcgtgacatgttagagccattagtgtatacccctgattcttca
ttgcagtctgagttgctcagctttattttggatcatgtcttcattgaacaggatgatgat
aataatagtgcagatggtcagcaagaggatgaagccagtaaaattgaagctctgcacaag
agaagaaatttacttgcagcattttgtaagctaattgtatatactgtggtggagatgaat
acagctgcagatatcttcaaacagtatatgaagtattataatgactatggagatatcatc
aaagaaacaatgagtaaaacaaggcagatagacaaaattcagtgtgctaagacccttatt
ctcagtctgcaacagctttttaatgaaatgatacaagaaaatggctataattttgataga
tcatcctctacatttagtggcataaaagaacttgctcgacgttttgctttaacttttgga
cttgatcagttgaaaacaagagaagccattgccatgctacacaaagatggcatagaattt
gcttttaaagagcctaatccgcaaggggagagccatccacctttaaatttggcatttctt
gatattctgagtgaattttcttctaaactacttcgacaagacaaaagaacagtgtatgtt
tacttggaaaagttcatgacctttcagatgtcactccgaagagaggatgtgtggcttcca
ctgatgtcttaccgaaattctttgctagctggtggtgatgatgacaccatgtcagtcatt
agtggaatcagcagccgggggtcaacagtacggagtaaaaaatcaaaaccatctacagga
aaacggaaagtggttgagggcatgcagctttcactcactgaagaaagtagtagtagtgac
agtatgtggttaagcagagaacaaacactgcacacccctgttatgatgcagacaccacaa
ctcacctccactattatgagagagcccaaaagattacggcctgaggatagcttcatgagt
gtttatccaatgcagactgaacatcatcaaacacctcttgattataatcggcgtggcaca
agcctaatggaagatgatgaagagccaattgtggaagatgttatgatgtcctcagaaggg
aggattgaggatcttaatgagggaatggattttgacaccatggatatagatttgccacca
tcaaagaacagacgagagagaacagaactgaagcctgatttctttgatccagcttcaatt
atggatgaatcagttcttggagtgtcaatgttttaa

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