NETWORK: N01533
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Entry
N01533 Network
Name
Disassembly of MCC
Definition
TRIP13+MAD2L1BP -| MCC -| ANAPC
Expanded
9319+9587 -| (4085+701+9184+991) -| (64682+29882+996+29945+51433+8881+51434+8697+10393+51529+246184)
Class
nt06515
Regulation of kinetochore-microtubule interactions
Type
Reference
Pathway
hsa04110
Cell cycle
Gene
9319
TRIP13; thyroid hormone receptor interactor 13
9587
MAD2L1BP; MAD2L1 binding protein
4085
MAD2L1; mitotic arrest deficient 2 like 1
701
BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
9184
BUB3; BUB3 mitotic checkpoint protein
991
CDC20; cell division cycle 20
64682
ANAPC1; anaphase promoting complex subunit 1
29882
ANAPC2; anaphase promoting complex subunit 2
996
CDC27; cell division cycle 27
29945
ANAPC4; anaphase promoting complex subunit 4
51433
ANAPC5; anaphase promoting complex subunit 5
8881
CDC16; cell division cycle 16
51434
ANAPC7; anaphase promoting complex subunit 7
8697
CDC23; cell division cycle 23
10393
ANAPC10; anaphase promoting complex subunit 10
51529
ANAPC11; anaphase promoting complex subunit 11
246184
CDC26; cell division cycle 26
Reference
PMID:
30341343
Authors
Kim DH, Han JS, Ly P, Ye Q, McMahon MA, Myung K, Corbett KD, Cleveland DW
Title
TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC.
Journal
Nat Commun 9:4354 (2018)
DOI:
10.1038/s41467-018-06774-1
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