KEGG T01001: 51433

Homo sapiens (human): 51433

Entry

51433             CDS       T01001

Symbol

ANAPC5, APC5

Name

(RefSeq) anaphase promoting complex subunit 5

K03352

anaphase-promoting complex subunit 5

Organism

hsa Homo sapiens (human)

Pathway

hsa04110

Cell cycle

hsa04114

Oocyte meiosis

hsa04120

Ubiquitin mediated proteolysis

hsa04657

IL-17 signaling pathway

hsa04914

Progesterone-mediated oocyte maturation

hsa05166

Human T-cell leukemia virus 1 infection

Network

nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06230  Cell cycle (cancer)
nt06512  Chromosome cohesion and segregation
nt06515  Regulation of kinetochore-microtubule interactions

Element

N00221

HTLV-1 Tax to spindle assembly checkpoint signaling

N00493

Spindle assembly checkpoint signaling

N01486

Cohesin dissociation in anaphase

N01533

Disassembly of MCC

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    51433 (ANAPC5)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    51433 (ANAPC5)
   04114 Oocyte meiosis
    51433 (ANAPC5)
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    51433 (ANAPC5)
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    51433 (ANAPC5)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    51433 (ANAPC5)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    51433 (ANAPC5)
   03036 Chromosome and associated proteins [BR:hsa03036]
    51433 (ANAPC5)
Ubiquitin system [BR:hsa04121]
Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   APC/C
    Other subunits
     51433 (ANAPC5)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
  Sister chromatid separation proteins
   APC/C complex
    51433 (ANAPC5)

SSDB

Motif

Pfam:

Apc5_N ANAPC5 TPR_12 TPR_10 TPR_2 TPR_19

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

12:complement(121308245..121354209)

AA seq 755 aa
MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRL
NQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFS
GTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKEL
NNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSL
RYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDI
SIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQ
GCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNS
IEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIA
LPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDK
GRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARL
YHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL

NT seq 2268 nt +upstreamnt +downstreamnt
atggccagcgtccacgagagcctctacttcaatcccatgatgaccaatggggttgtgcac
gccaatgtgttcggcatcaaggactgggtgacgccgtacaagatcgcggtgctggtgctg
ctgaacgagatgagccgcacaggcgagggcgccgtcagcctcatggagcggcggaggctc
aaccagctgctcctgcccctgctgcagggcccagatattacactgtcaaaactttacaag
ttaattgaagagtcttgtccacagctggcaaattcagtgcagatcagaatcaaactgatg
gctgaaggcgagttgaaggatatggaacagttttttgatgacctttcagattctttctct
ggaactgaaccagaggttcacaaaacaagtgtagtaggtttgtttctgcgtcacatgatc
ttggcctacagtaagctttctttcagccaagtgtttaaactgtacactgcccttcagcag
tacttccagaatggtgagaaaaagacagtggaggatgctgatatggaactgaccagtaga
gatgagggtgaaagaaaaatggaaaaagaagaacttgatgtatctgtaagagaagaggag
gtatcttgcagtgggcctctgtcccaaaaacaagcagaattttttctttctcaacaggct
tctttgctaaagaatgatgagactaaggccctcactccagcttccttgcagaaggaatta
aacaatttgttgaaatttaatcctgattttgctgaagcgcattatctcagctacttaaac
aacctccgtgtccaagatgttttcagttcaacacacagtctcctccattattttgatcgt
ctgattcttaccggagccgaaagcaaaagtaatggggaagagggctatggccggagcttg
agatacgccgctctgaatcttgccgccctgcactgccgcttcggtcactatcaacaggca
gagctcgccctgcaggaggcaattaggattgcccaggagtccaacgatcacgtgtgtctc
cagcactgtttgagctggctttatgtgctggggcagaagagatccgatagctatgttctg
ctggagcattctgtgaagaaggcagtacattttgggttaccgtacctcgcctccctggga
atacagtcccttgttcaacagagagcttttgctgggaagacggcaaacaagctgatggat
gccctaaaggactccgacctcctgcactggaaacacagcctgtcagagctcatcgatatc
agcatcgcacagaaaacggccatctggaggctgtatggccgcagcaccatggcactgcaa
caggcccagatgttgctgagcatgaacagcctggaggcggtgaatgcgggcgtgcagcag
aacaacacagagtcctttgctgtcgcactctgccacctcgcagagctacacgcggagcag
ggctgttttgctgcagcttctgaagtgttaaagcacttgaaggaacgatttccgcctaat
agtcagcacgcccagttatggatgctatgtgatcaaaaaatacagtttgacagagcaatg
aatgatggcaaatatcatttggctgattcacttgttacaggaatcacagctctcaatagc
atagagggtgtttataggaaagcggttgtattacaagctcagaaccaaatgtcagaggca
cataagcttttacaaaaattgttggttcattgtcagaaactgaagaacacagaaatggtg
atcagtgtcctactgtccgtggcagagctgtactggcgatcttcctcccctaccatcgcg
ctgcccatgctcctgcaggctctggccctctccaaggagtaccggttacagtacttggcc
tctgaaacagtgctgaacttggcttttgcgcagctcattcttggaatcccagaacaggcc
ttaagtcttctccacatggccatcgagcccatcttggctgacggggctatcctggacaaa
ggtcgtgccatgttcttagtggccaagtgccaggtggcttcagcagcttcctacgatcag
ccgaagaaagcagaagctctggaggctgccatcgagaacctcaatgaagccaagaactat
tttgcaaaggttgactgcaaagagcgcatcagggacgtcgtttacttccaggccagactc
taccataccctggggaagacccaggagaggaaccggtgtgcgatgctcttccggcagctg
catcaggagctgccctctcatggggtacccttgataaaccatctctag

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