KEGG   NETWORK: N01551
Entry
N01551                      Network                                
Name
Serotonin metabolism
Definition
Trp -- TPH1/2 >> DDC -> Serotonin -- MAO -> 5-HIAL
  Expanded
C00078 -- (7166,121278) >> 1644 -> C00780 -- (4128,4129) -> C05634
Class
nt06028 Dopamine and serotonin metabolism
nt06544 Neuroactive ligand signaling
Type
Reference
Pathway
hsa00380  Tryptophan metabolism
hsa04726  Serotonergic synapse
Gene
7166  TPH1; tryptophan hydroxylase 1
121278  TPH2; tryptophan hydroxylase 2
1644  DDC; dopa decarboxylase
4128  MAOA; monoamine oxidase A
4129  MAOB; monoamine oxidase B
Metabolite
C00078  L-Tryptophan
C00780  Serotonin
C05634  5-Hydroxyindoleacetaldehyde
Reference
PMID:18651566
  Authors
Jonnakuty C, Gragnoli C
  Title
What do we know about serotonin?
  Journal
J Cell Physiol 217:301-6 (2008)
DOI:10.1002/jcp.21533
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