| Entry |
|
|---|
| Name |
TNF-RIPK1/3 signaling pathway
|
|---|
| Definition |
TNF -> TNFRSF1A -> (TRAF2/5+TRADD+RIPK1+RIPK3) |
|---|
| Expanded |
7124 -> 7132 -> ((7186+7188)+8717+8737+11035) |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
|
|---|
| Gene |
| 7124 | TNF; tumor necrosis factor |
| 7132 | TNFRSF1A; TNF receptor superfamily member 1A |
| 7186 | TRAF2; TNF receptor associated factor 2 |
| 7188 | TRAF5; TNF receptor associated factor 5 |
| 8717 | TRADD; TNFRSF1A associated via death domain |
| 8737 | RIPK1; receptor interacting serine/threonine kinase 1 |
| 11035 | RIPK3; receptor interacting serine/threonine kinase 3 |
|
|---|
| Reference |
|
|---|
| Authors |
Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G |
|---|
| Title |
Molecular mechanisms of necroptosis: an ordered cellular explosion. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Brenner D, Blaser H, Mak TW |
|---|
| Title |
Regulation of tumour necrosis factor signalling: live or let die. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Conrad M, Angeli JP, Vandenabeele P, Stockwell BR |
|---|
| Title |
Regulated necrosis: disease relevance and therapeutic opportunities. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
