| Entry |
|
|---|
| Name |
INS-AKT signaling pathway
|
|---|
| Definition |
INS -> INSR -> IRS -> PI3K |
|---|
| Expanded |
3630 -> 3643 -> (3667,8660,8471) -> (5290,5291,5293,5295,5296,8503) |
|---|
| Class |
|
|---|
| Type |
Reference
|
|---|
| Pathway |
| hsa04923 | Regulation of lipolysis in adipocytes |
|
|---|
| Gene |
| 3643 | INSR; insulin receptor |
| 3667 | IRS1; insulin receptor substrate 1 |
| 8660 | IRS2; insulin receptor substrate 2 |
| 8471 | IRS4; insulin receptor substrate 4 |
| 5290 | PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| 5291 | PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
| 5293 | PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
| 5295 | PIK3R1; phosphoinositide-3-kinase regulatory subunit 1 |
| 5296 | PIK3R2; phosphoinositide-3-kinase regulatory subunit 2 |
| 8503 | PIK3R3; phosphoinositide-3-kinase regulatory subunit 3 |
|
|---|
| Reference |
|
|---|
| Authors |
Grabner GF, Xie H, Schweiger M, Zechner R |
|---|
| Title |
Lipolysis: cellular mechanisms for lipid mobilization from fat stores. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Kushi R, Hirota Y, Ogawa W |
|---|
| Title |
Insulin resistance and exaggerated insulin sensitivity triggered by single-gene mutations in the insulin signaling pathway. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Li M, Chi X, Wang Y, Setrerrahmane S, Xie W, Xu H |
|---|
| Title |
Trends in insulin resistance: insights into mechanisms and therapeutic strategy. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
