Entry |
|
Name |
CaMK2-p38-MK2-ALOX5 pathway
|
Definition |
CAMK2 -> p38 -> MK2 -- ALOX5(cyto) -> ALOX5(nuclear) |
Expanded |
(815,816,817,818) -> (1432,5600,5603,6300) -> 9261 -- 240 -> 240 |
Class |
|
Type |
Reference
|
Pathway |
|
Gene |
815 | CAMK2A; calcium/calmodulin dependent protein kinase II alpha |
816 | CAMK2B; calcium/calmodulin dependent protein kinase II beta |
817 | CAMK2D; calcium/calmodulin dependent protein kinase II delta |
818 | CAMK2G; calcium/calmodulin dependent protein kinase II gamma |
1432 | MAPK14; mitogen-activated protein kinase 14 |
5600 | MAPK11; mitogen-activated protein kinase 11 |
5603 | MAPK13; mitogen-activated protein kinase 13 |
6300 | MAPK12; mitogen-activated protein kinase 12 |
9261 | MAPKAPK2; MAPK activated protein kinase 2 |
240 | ALOX5; arachidonate 5-lipoxygenase |
|
Reference |
|
Authors |
Cai B, Kasikara C, Doran AC, Ramakrishnan R, Birge RB, Tabas I |
Title |
MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity. |
Journal |
|
Reference |
|
Authors |
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M |
Title |
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease. |
Journal |
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LinkDB |
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