Homo sapiens (human): 817
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Entry
817 CDS
T01001
Symbol
CAMK2D, CAMKD
Name
(RefSeq) calcium/calmodulin dependent protein kinase II delta
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
817 (CAMK2D)
04310 Wnt signaling pathway
817 (CAMK2D)
04066 HIF-1 signaling pathway
817 (CAMK2D)
04020 Calcium signaling pathway
817 (CAMK2D)
04024 cAMP signaling pathway
817 (CAMK2D)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
817 (CAMK2D)
09143 Cell growth and death
04114 Oocyte meiosis
817 (CAMK2D)
04217 Necroptosis
817 (CAMK2D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
817 (CAMK2D)
04922 Glucagon signaling pathway
817 (CAMK2D)
04912 GnRH signaling pathway
817 (CAMK2D)
04921 Oxytocin signaling pathway
817 (CAMK2D)
04916 Melanogenesis
817 (CAMK2D)
04925 Aldosterone synthesis and secretion
817 (CAMK2D)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
817 (CAMK2D)
09154 Digestive system
04971 Gastric acid secretion
817 (CAMK2D)
09156 Nervous system
04725 Cholinergic synapse
817 (CAMK2D)
04728 Dopaminergic synapse
817 (CAMK2D)
04720 Long-term potentiation
817 (CAMK2D)
04722 Neurotrophin signaling pathway
817 (CAMK2D)
09157 Sensory system
04740 Olfactory transduction
817 (CAMK2D)
04750 Inflammatory mediator regulation of TRP channels
817 (CAMK2D)
09158 Development and regeneration
04360 Axon guidance
817 (CAMK2D)
09159 Environmental adaptation
04713 Circadian entrainment
817 (CAMK2D)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
817 (CAMK2D)
05205 Proteoglycans in cancer
817 (CAMK2D)
09162 Cancer: specific types
05214 Glioma
817 (CAMK2D)
09171 Infectious disease: bacterial
05152 Tuberculosis
817 (CAMK2D)
09164 Neurodegenerative disease
05012 Parkinson disease
817 (CAMK2D)
05022 Pathways of neurodegeneration - multiple diseases
817 (CAMK2D)
09165 Substance dependence
05031 Amphetamine addiction
817 (CAMK2D)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
817 (CAMK2D)
05415 Diabetic cardiomyopathy
817 (CAMK2D)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
817 (CAMK2D)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
817 (CAMK2D)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
817 (CAMK2D)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
817 (CAMK2D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
Pkinase_fungal
Kdo
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
817
NCBI-ProteinID:
NP_001212
OMIM:
607708
HGNC:
1462
Ensembl:
ENSG00000145349
UniProt:
Q13557
Structure
PDB
LinkDB
All DBs
Position
4:complement(113451032..113761738)
Genome browser
AA seq
499 aa
AA seq
DB search
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT
VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA
INNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVH
LVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPP
CIPNGKENFSGGTSLWQNI
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atggcttcgaccacaacctgcaccaggttcacggacgagtatcagcttttcgaggagctt
ggaaagggggcattctcagtggtgagaagatgtatgaaaattcctactggacaagaatat
gctgccaaaattatcaacaccaaaaagctttctgctagggatcatcagaaactagaaaga
gaagctagaatctgccgtcttttgaagcaccctaatattgtgcgacttcatgatagcata
tcagaagagggctttcactacttggtgtttgatttagttactggaggtgaactgtttgaa
gacatagtggcaagagaatactacagtgaagctgatgccagtcattgtatacagcagatt
ctagaaagtgttaatcattgtcacctaaatggcatagttcacagggacctgaagcctgag
aatttgcttttagctagcaaatccaagggagcagctgtgaaattggcagactttggctta
gccatagaagttcaaggggaccagcaggcgtggtttggttttgctggcacacctggatat
ctttctccagaagttttacgtaaagatccttatggaaagccagtggatatgtgggcatgt
ggtgtcattctctatattctacttgtggggtatccacccttctgggatgaagaccaacac
agactctatcagcagatcaaggctggagcttatgattttccatcaccagaatgggacacg
gtgactcctgaagccaaagacctcatcaataaaatgcttactatcaaccctgccaaacgc
atcacagcctcagaggcactgaagcacccatggatctgtcaacgttctactgttgcttcc
atgatgcacagacaggagactgtagactgcttgaagaaatttaatgctagaagaaaacta
aagggtgccatcttgacaactatgctggctacaaggaatttctcagcagccaagagtttg
ttgaagaaaccagatggagtaaaggagtcaactgagagttcaaatacaacaattgaggat
gaagatgtgaaagcacgaaagcaagagattatcaaagtcactgaacaactgatcgaagct
atcaacaatggggactttgaagcctacacaaaaatctgtgacccaggccttactgctttt
gaacctgaagctttgggtaatttagtggaagggatggattttcaccgattctactttgaa
aatgctttgtccaaaagcaataaaccaatccacactattattctaaaccctcatgtacat
ctggtaggggatgatgccgcctgcatagcatatattaggctcacacagtacatggatggc
agtggaatgccaaagacaatgcagtcagaagagactcgtgtgtggcaccgccgggatgga
aagtggcagaatgttcattttcatcgctcggggtcaccaacagtacccatcaagccaccc
tgtattccaaatgggaaagaaaacttctcaggaggcacctctttgtggcaaaacatctaa
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