Homo sapiens (human): 818
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Entry
818 CDS
T01001
Symbol
CAMK2G, CAMK, CAMK-II, CAMKG, MRD59
Name
(RefSeq) calcium/calmodulin dependent protein kinase II gamma
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
818 (CAMK2G)
04310 Wnt signaling pathway
818 (CAMK2G)
04066 HIF-1 signaling pathway
818 (CAMK2G)
04020 Calcium signaling pathway
818 (CAMK2G)
04024 cAMP signaling pathway
818 (CAMK2G)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
818 (CAMK2G)
09143 Cell growth and death
04114 Oocyte meiosis
818 (CAMK2G)
04217 Necroptosis
818 (CAMK2G)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
818 (CAMK2G)
04922 Glucagon signaling pathway
818 (CAMK2G)
04912 GnRH signaling pathway
818 (CAMK2G)
04921 Oxytocin signaling pathway
818 (CAMK2G)
04916 Melanogenesis
818 (CAMK2G)
04925 Aldosterone synthesis and secretion
818 (CAMK2G)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
818 (CAMK2G)
09154 Digestive system
04971 Gastric acid secretion
818 (CAMK2G)
09156 Nervous system
04725 Cholinergic synapse
818 (CAMK2G)
04728 Dopaminergic synapse
818 (CAMK2G)
04720 Long-term potentiation
818 (CAMK2G)
04722 Neurotrophin signaling pathway
818 (CAMK2G)
09157 Sensory system
04740 Olfactory transduction
818 (CAMK2G)
04750 Inflammatory mediator regulation of TRP channels
818 (CAMK2G)
09158 Development and regeneration
04360 Axon guidance
818 (CAMK2G)
09159 Environmental adaptation
04713 Circadian entrainment
818 (CAMK2G)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
818 (CAMK2G)
05205 Proteoglycans in cancer
818 (CAMK2G)
09162 Cancer: specific types
05214 Glioma
818 (CAMK2G)
09171 Infectious disease: bacterial
05152 Tuberculosis
818 (CAMK2G)
09164 Neurodegenerative disease
05012 Parkinson disease
818 (CAMK2G)
05022 Pathways of neurodegeneration - multiple diseases
818 (CAMK2G)
09165 Substance dependence
05031 Amphetamine addiction
818 (CAMK2G)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
818 (CAMK2G)
05415 Diabetic cardiomyopathy
818 (CAMK2G)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
818 (CAMK2G)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
818 (CAMK2G)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
818 (CAMK2G)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
818 (CAMK2G)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
Pkinase_fungal
Kdo
ABC1
SnoaL_4
Motif
Other DBs
NCBI-GeneID:
818
NCBI-ProteinID:
NP_001191421
OMIM:
602123
HGNC:
1463
Ensembl:
ENSG00000148660
UniProt:
Q13555
Structure
PDB
LinkDB
All DBs
Position
10:complement(73812501..73874555)
Genome browser
AA seq
539 aa
AA seq
DB search
MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER
EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI
LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY
LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL
KGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKPQSNNKNSL
VSPAQEPAPLQTAMEPQTTVVHNATDGIKGSTESCNTTTEDEDLKVRKQEIIKITEQLIE
AINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPIHTTILNPHV
HVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWLNVHYHCSGAPAAPLQ
NT seq
1620 nt
NT seq
+upstream
nt +downstream
nt
atggccaccaccgccacctgcacccgtttcaccgacgactaccagctcttcgaggagctt
ggcaagggtgctttctctgtggtccgcaggtgtgtgaagaaaacctccacgcaggagtac
gcagcaaaaatcatcaataccaagaagttgtctgcccgggatcaccagaaactagaacgt
gaggctcggatatgtcgacttctgaaacatccaaacatcgtgcgcctccatgacagtatt
tctgaagaagggtttcactacctcgtgtttgaccttgttaccggcggggagctgtttgaa
gacattgtggccagagagtactacagtgaagcagatgccagccactgtatacatcagatt
ctggagagtgttaaccacatccaccagcatgacatcgtccacagggacctgaagcctgag
aacctgctgctggcgagtaaatgcaagggtgccgccgtcaagctggctgattttggccta
gccatcgaagtacagggagagcagcaggcttggtttggttttgctggcaccccaggttac
ttgtcccctgaggtcttgaggaaagatccctatggaaaacctgtggatatctgggcctgc
ggggtcatcctgtatatcctcctggtgggctatcctcccttctgggatgaggatcagcac
aagctgtatcagcagatcaaggctggagcctatgatttcccatcaccagaatgggacacg
gtaactcctgaagccaagaacttgatcaaccagatgctgaccataaacccagcaaagcgc
atcacggctgaccaggctctcaagcacccgtgggtctgtcaacgatccacggtggcatcc
atgatgcatcgtcaggagactgtggagtgtttgcgcaagttcaatgcccggagaaaactg
aagggtgccatcctcacgaccatgcttgtctccaggaacttctcagttggcaggcagagc
tccgcccccgcctcgcctgccgcgagcgccgccggcctggccgggcaagctgccaaaagc
ctattgaacaagaagtcggatggcggtgtcaagccacagagcaacaacaaaaacagtctc
gtaagcccagcccaagagcccgcgcccttgcagacggccatggagccacaaaccactgtg
gtacacaacgctacagatgggatcaagggctccacagagagctgcaacaccaccacagaa
gatgaggacctcaaagtgcgaaaacaggagatcattaagattacagaacagctgattgaa
gccatcaacaatggggactttgaggcctacacgaagatttgtgatccaggcctcacttcc
tttgagcctgaggcccttggtaacctcgtggaggggatggatttccataagttttacttt
gagaatctcctgtccaagaacagcaagcctatccataccaccatcctaaacccacacgtc
cacgtgattggggaggacgcagcgtgcatcgcctacatccgcctcacccagtacatcgac
gggcagggtcggcctcgcaccagccagtcagaagagacccgggtctggcaccgtcgggat
ggcaagtggctcaatgtccactatcactgctcaggggcccctgccgcaccgctgcagtga
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