| Entry |
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| Name |
FGF23-NCC/NPT signaling pathway
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| Definition |
FGF23 -> (FGFR1+KL) -> ERK -> SGK1 -> WNK1/4 -> NCC -> (Na+,CL-)(cyto) |
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| Expanded |
8074 -> (2260+9365) -> 5594,5595 -> 6446 -> 65125,65266 -> 6559 -> (C01330,C00698) |
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| Class |
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| Type |
Reference
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| Pathway |
| hsa04928 | Parathyroid hormone synthesis, secretion and action |
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| Gene |
| 8074 | FGF23; fibroblast growth factor 23 |
| 2260 | FGFR1; fibroblast growth factor receptor 1 |
| 5594 | MAPK1; mitogen-activated protein kinase 1 |
| 5595 | MAPK3; mitogen-activated protein kinase 3 |
| 6446 | SGK1; serum/glucocorticoid regulated kinase 1 |
| 65125 | WNK1; WNK lysine deficient protein kinase 1 |
| 65266 | WNK4; WNK lysine deficient protein kinase 4 |
| 6559 | SLC12A3; solute carrier family 12 member 3 |
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| Metabolite |
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| Reference |
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| Authors |
Andrukhova O, Streicher C, Zeitz U, Erben RG |
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| Title |
Fgf23 and parathyroid hormone signaling interact in kidney and bone. |
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| Journal |
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| Reference |
|
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| Authors |
Agoro R, Ni P, Noonan ML, White KE |
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| Title |
Osteocytic FGF23 and Its Kidney Function. |
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| Journal |
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| Reference |
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| Authors |
Erben RG, Andrukhova O |
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| Title |
FGF23-Klotho signaling axis in the kidney. |
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| Journal |
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| Reference |
|
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| Authors |
Takashi Y, Fukumoto S |
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| Title |
FGF23 beyond Phosphotropic Hormone. |
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| Journal |
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| LinkDB |
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