Homo sapiens (human): 6446
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Entry
6446 CDS
T01001
Symbol
SGK1, SGK
Name
(RefSeq) serum/glucocorticoid regulated kinase 1
KO
K13302
serum/glucocorticoid-regulated kinase 1 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04068
FoxO signaling pathway
hsa04150
mTOR signaling pathway
hsa04151
PI3K-Akt signaling pathway
hsa04960
Aldosterone-regulated sodium reabsorption
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
6446 (SGK1)
04151 PI3K-Akt signaling pathway
6446 (SGK1)
04150 mTOR signaling pathway
6446 (SGK1)
09150 Organismal Systems
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
6446 (SGK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
6446 (SGK1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
6446 (SGK1)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
SGK family [OT]
6446 (SGK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_C
ABC1
Kdo
PX
APH
Motif
Other DBs
NCBI-GeneID:
6446
NCBI-ProteinID:
NP_005618
OMIM:
602958
HGNC:
10810
Ensembl:
ENSG00000118515
Pharos:
O00141
(Tchem)
UniProt:
O00141
Structure
PDB
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All DBs
Position
6:complement(134169256..134318112)
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AA seq
431 aa
AA seq
DB search
MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQSILKI
SQPQEPELMNANPSPPPSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAE
EVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYIN
GGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLDSQGHIVLTD
FGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSR
NTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKSHVFFSLINW
DDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASVKEAAEAFLG
FSYAPPTDSFL
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgacggtgaaaactgaggctgctaagggcaccctcacttactccaggatgaggggcatg
gtggcaattctcatcgctttcatgaagcagaggaggatgggtctgaacgactttattcag
aagattgccaataactcctatgcatgcaaacaccctgaagttcagtccatcttgaagatc
tcccaacctcaggagcctgagcttatgaatgccaacccttctcctccaccaagtccttct
cagcaaatcaaccttggcccgtcgtccaatcctcatgctaaaccatctgactttcacttc
ttgaaagtgatcggaaagggcagttttggaaaggttcttctagcaagacacaaggcagaa
gaagtgttctatgcagtcaaagttttacagaagaaagcaatcctgaaaaagaaagaggag
aagcatattatgtcggagcggaatgttctgttgaagaatgtgaagcaccctttcctggtg
ggccttcacttctctttccagactgctgacaaattgtactttgtcctagactacattaat
ggtggagagttgttctaccatctccagagggaacgctgcttcctggaaccacgggctcgt
ttctatgctgctgaaatagccagtgccttgggctacctgcattcactgaacatcgtttat
agagacttaaaaccagagaatattttgctagattcacagggacacattgtccttactgac
ttcggactctgcaaggagaacattgaacacaacagcacaacatccaccttctgtggcacg
ccggagtatctcgcacctgaggtgcttcataagcagccttatgacaggactgtggactgg
tggtgcctgggagctgtcttgtatgagatgctgtatggcctgccgcctttttatagccga
aacacagctgaaatgtacgacaacattctgaacaagcctctccagctgaaaccaaatatt
acaaattccgcaagacacctcctggagggcctcctgcagaaggacaggacaaagcggctc
ggggccaaggatgacttcatggagattaagagtcatgtcttcttctccttaattaactgg
gatgatctcattaataagaagattactcccccttttaacccaaatgtgagtgggcccaac
gacctacggcactttgaccccgagtttaccgaagagcctgtccccaactccattggcaag
tcccctgacagcgtcctcgtcacagccagcgtcaaggaagctgccgaggctttcctaggc
ttttcctatgcgcctcccacggactctttcctctga
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