KEGG   NETWORK: N01948
Entry
N01948                      Network                                
Name
PTPRD interactions
Definition
(HSPG,PTPRF/D/S,NGL3,SALM3/5,IL1RAPL1,IL1RAP,NLGN3,SLITRK) == PTPRD -> (PPFIA,CASKIN+CASK,TRIO)
  Expanded
((6382,6383,9672,6385,2817,221914,2719,2239,2262,10082,3339,375790,1306,80781),(5792,5789,5802),94030,(78999,145581),11141,3556,54413,(114798,84631,139065,26050,84189)) == 5789 -> ((8500,8499,8541,8497),(57524,57513+8573),7204)
Class
nt06546 IgSF CAM signaling
Type
Reference
Pathway
hsa04517 IGSF CAM signaling   
Gene
6382  SDC1; syndecan 1
6383  SDC2; syndecan 2
9672  SDC3; syndecan 3
6385  SDC4; syndecan 4
2817  GPC1; glypican 1
221914  GPC2; glypican 2
2719  GPC3; glypican 3
2239  GPC4; glypican 4
2262  GPC5; glypican 5
10082  GPC6; glypican 6
3339  HSPG2; heparan sulfate proteoglycan 2
375790  AGRN; agrin
1306  COL15A1; collagen type XV alpha 1 chain
80781  COL18A1; collagen type XVIII alpha 1 chain
5792  PTPRF; protein tyrosine phosphatase receptor type F
5789  PTPRD; protein tyrosine phosphatase receptor type D
5802  PTPRS; protein tyrosine phosphatase receptor type S
94030  LRRC4B; leucine rich repeat containing 4B
78999  LRFN4; leucine rich repeat and fibronectin type III domain containing 4
145581  LRFN5; leucine rich repeat and fibronectin type III domain containing 5
11141  IL1RAPL1; interleukin 1 receptor accessory protein like 1
3556  IL1RAP; interleukin 1 receptor accessory protein
54413  NLGN3; neuroligin 3
114798  SLITRK1; SLIT and NTRK like family member 1
84631  SLITRK2; SLIT and NTRK like family member 2
139065  SLITRK4; SLIT and NTRK like family member 4
26050  SLITRK5; SLIT and NTRK like family member 5
84189  SLITRK6; SLIT and NTRK like family member 6
8500  PPFIA1; PPFI scaffold protein A1
8499  PPFIA2; PPFI scaffold protein A2
8541  PPFIA3; PPFI scaffold protein A3
8497  PPFIA4; PPFI scaffold protein A4
57524  CASKIN1; CASK interacting protein 1
57513  CASKIN2; CASK interacting protein 2
8573  CASK; calcium/calmodulin dependent serine protein kinase
7204  TRIO; trio Rho guanine nucleotide exchange factor
Reference
PMID:15674434
  Authors
Chagnon MJ, Uetani N, Tremblay ML
  Title
Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases.
  Journal
Biochem Cell Biol 82:664-75 (2004)
DOI:10.1139/o04-120
Reference
PMID:34966732
  Authors
Cornejo F, Cortes BI, Findlay GM, Cancino GI
  Title
LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain.
  Journal
Front Cell Dev Biol 9:659951 (2021)
DOI:10.3389/fcell.2021.659951
Reference
PMID:23835198
  Authors
Takahashi H, Craig AM
  Title
Protein tyrosine phosphatases PTPdelta, PTPsigma, and LAR: presynaptic hubs for synapse organization.
  Journal
Trends Neurosci 36:522-34 (2013)
DOI:10.1016/j.tins.2013.06.002
Reference
PMID:34654889
  Authors
Pehkonen H, de Curtis I, Monni O
  Title
Liprins in oncogenic signaling and cancer cell adhesion.
  Journal
Oncogene 40:6406-6416 (2021)
DOI:10.1038/s41388-021-02048-1
Reference
PMID:23916315
  Authors
Um JW, Ko J
  Title
LAR-RPTPs: synaptic adhesion molecules that shape synapse development.
  Journal
Trends Cell Biol 23:465-75 (2013)
DOI:10.1016/j.tcb.2013.07.004
Reference
PMID:27017006
  Authors
Han KA, Jeon S, Um JW, Ko J
  Title
Emergent Synapse Organizers: LAR-RPTPs and Their Companions.
  Journal
Int Rev Cell Mol Biol 324:39-65 (2016)
DOI:10.1016/bs.ircmb.2016.01.002
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