| Entry |
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| Name |
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| Definition |
(JAM1,(ITGA5+ITGB3),LFA1) == JAM1 -> (AFDN,RAPGEF2/6),(PARD3/6+PRKCI),TJP1/2 |
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| Expanded |
(50848,(3678+3690),(3683+3689)) == 50848 -> (4301,(9693,51735)),((56288,50855,84612,84552)+5584),(7082,9414) |
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| Class |
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| Type |
Reference
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| Pathway |
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| Gene |
| 3678 | ITGA5; integrin subunit alpha 5 |
| 3690 | ITGB3; integrin subunit beta 3 |
| 3683 | ITGAL; integrin subunit alpha L |
| 3689 | ITGB2; integrin subunit beta 2 |
| 4301 | AFDN; afadin, adherens junction formation factor |
| 9693 | RAPGEF2; Rap guanine nucleotide exchange factor 2 |
| 51735 | RAPGEF6; Rap guanine nucleotide exchange factor 6 |
| 56288 | PARD3; par-3 family cell polarity regulator |
| 50855 | PARD6A; par-6 family cell polarity regulator alpha |
| 84612 | PARD6B; par-6 family cell polarity regulator beta |
| 84552 | PARD6G; par-6 family cell polarity regulator gamma |
| 5584 | PRKCI; protein kinase C iota |
| 7082 | TJP1; tight junction protein 1 |
| 9414 | TJP2; tight junction protein 2 |
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| Reference |
|
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| Authors |
Garrido-Urbani S, Bradfield PF, Imhof BA |
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| Title |
Tight junction dynamics: the role of junctional adhesion molecules (JAMs). |
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| Journal |
|
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| Reference |
|
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| Authors |
Wibbe N, Ebnet K |
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| Title |
Cell Adhesion at the Tight Junctions: New Aspects and New Functions. |
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| Journal |
|
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| Reference |
|
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| Authors |
Ebnet K |
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| Title |
Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development. |
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| Journal |
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| LinkDB |
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