KEGG   NETWORK: N01964
Entry
N01964                      Network                                
Name
pre U1 snRNP import and U1 snRNP formation
Definition
m7G-preU1snRNP -- TGS1 -> TmG-preU1snRNP -- SNUPN+KPNB1 -> TmG-preU1snRNP(nucleus) == (SNRPA+SNRPC)
  Expanded
(26871+6625+6628+6634+6632+6633+6635+6636+6637) -- 96764 -> (26871+6625+6628+6634+6632+6633+6635+6636+6637) -- 10073+3837 -> (26871+6625+6628+6634+6632+6633+6635+6636+6637) == (6626+6631)
Class
nt06547 Spliceosome
Type
Reference
Pathway
hsa03040  Spliceosome
Gene
26871  RNU1-1; RNA, U1 small nuclear 1
6625  SNRNP70; small nuclear ribonucleoprotein U1 subunit 70
6628  SNRPB; small nuclear ribonucleoprotein polypeptides B and B1
6634  SNRPD3; small nuclear ribonucleoprotein D3 polypeptide
6632  SNRPD1; small nuclear ribonucleoprotein D1 polypeptide
6633  SNRPD2; small nuclear ribonucleoprotein D2 polypeptide
6635  SNRPE; small nuclear ribonucleoprotein polypeptide E
6636  SNRPF; small nuclear ribonucleoprotein polypeptide F
6637  SNRPG; small nuclear ribonucleoprotein polypeptide G
96764  TGS1; trimethylguanosine synthase 1
10073  SNUPN; snurportin 1
3837  KPNB1; karyopherin subunit beta 1
6626  SNRPA; small nuclear ribonucleoprotein polypeptide A
6631  SNRPC; small nuclear ribonucleoprotein polypeptide C
Reference
PMID:38459794
  Authors
Campagne S
  Title
U1 snRNP Biogenesis Defects in Neurodegenerative Diseases.
  Journal
Chembiochem 25:e202300864 (2024)
DOI:10.1002/cbic.202300864
Reference
PMID:26118337
  Authors
Piecyk K, Niedzwiecka A, Ferenc-Mrozek A, Lukaszewicz M, Darzynkiewicz E, Jankowska-Anyszka M
  Title
How to find the optimal partner--studies of snurportin 1 interactions with U snRNA 5' TMG-cap analogues containing modified 2-amino group of  7-methylguanosine.
  Journal
Bioorg Med Chem 23:4660-4668 (2015)
DOI:10.1016/j.bmc.2015.05.054
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