KEGG   REACTION: R02017
Entry
R02017                      Reaction                               
Name
2'-deoxyadenosine 5'-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
Definition
dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP
Equation
C00206 + C00343 + C00001 <=> C00342 + C00008
Reaction class
RC00013  C00342_C00343
RC00613  C00008_C00206
Enzyme
1.17.4.1
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01232  Nucleotide metabolism
Module
M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1
     R02017  dADP + Thioredoxin disulfide + H2O <=> Thioredoxin + ADP
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.17.4.1
   R04294  2'-Deoxyribonucleoside diphosphate <=> Ribonucleoside diphosphate
    R02017  dADP <=> ADP
Orthology
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
K00526  ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
K10807  ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808  ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
Other DBs
RHEA: 28037
LinkDB

KEGG   RCLASS: RC00613
Entry
RC00613                     RClass                                 
Definition
C1x-C1y:*-O1a:C1y+C1y-C1y+C1y
Reactant pair
C00002_C00131    C00008_C00206    C00015_C01346
C00035_C00361    C00044_C00286    C00063_C00458
C00075_C00460    C00112_C00705    C00299_C00526
C00677_C03802    C00688_C11927    C03723_C04232
C03802_C04283    C05465_C15516    C11875_C11876
C12112_C21293    C17712_C21264    C20528_C20542
C21748_C21750
Related class
Reaction
R01879 R02014 R02017 R02018 R02019 R02020 R02022 R02023
R02024 R04294 R04315 R06296 R06445 R07205 R08363 R08364
R10571 R11287 R11340 R11592 R11633 R11634 R11635 R11636
R11893
Enzyme
1.1.98.6        1.14.11.3       1.14.11.52      1.14.14.57      
1.14.14.107     1.17.4.1        1.17.4.2
Pathway
rn00230  Purine metabolism
rn00240  Pyrimidine metabolism
rn00403  Indole diterpene alkaloid biosynthesis
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn00525  Acarbose and validamycin biosynthesis
rn00904  Diterpenoid biosynthesis
rn00983  Drug metabolism - other enzymes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01232  Nucleotide metabolism
Orthology
K00524  ribonucleotide reductase, class II [EC:1.17.4.2]
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
K00526  ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
K00527  ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2]
K04123  ent-kaurenoic acid monooxygenase [EC:1.14.14.107]
K10807  ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808  ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K20586  oxidoreductase
K20587  dehydrogenase
K21036  validamycin A dioxygenase [EC:1.14.11.52]
K21636  ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]

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