KEGG   REACTION: R03058
Entry
R03058                      Reaction                               
Name
arachidonate:oxygen 5-oxidoreductase
Definition
5(S)-HPETE <=> Leukotriene A4 + H2O
Equation
Comment
second step of two-step reaction (R08527, R01595+R03058)
following after R01595
Reaction class
RC00839  C00909_C05356
Enzyme
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.34
     R03058  5(S)-HPETE <=> Leukotriene A4 + H2O
Orthology
K00461  arachidonate 5-lipoxygenase [EC:1.13.11.34]
Other DBs
RHEA: 17964
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