KEGG   REACTION: R08527
Entry
R08527                      Reaction                               

Name
Arachidonate 5-lipoxygenase
Definition
Arachidonate + Oxygen <=> Leukotriene A4 + H2O
Equation
Comment
two-step reaction (R01595+R03058)
Reaction class
RC02139  C00219_C00909
Enzyme
Orthology
K00461  arachidonate 5-lipoxygenase [EC:1.13.11.34]
Other DBs
RHEA: 32310
LinkDB

KEGG   REACTION: R01595
Entry
R01595                      Reaction                               

Name
Arachidonate:oxygen 5-oxidoreductase
Definition
Arachidonate + Oxygen <=> 5(S)-HPETE
Equation
Comment
first step of two-step reaction (R08527, R01595+R03058)
subsequently R03058
Reaction class
RC00561  C00219_C05356
Enzyme
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Orthology
K00461  arachidonate 5-lipoxygenase [EC:1.13.11.34]
Other DBs
RHEA: 17488
LinkDB

KEGG   REACTION: R03058
Entry
R03058                      Reaction                               

Name
arachidonate:oxygen 5-oxidoreductase
Definition
5(S)-HPETE <=> Leukotriene A4 + H2O
Equation
Comment
second step of two-step reaction (R08527, R01595+R03058)
following after R01595
Reaction class
RC00839  C00909_C05356
Enzyme
Pathway
rn00590  Arachidonic acid metabolism
rn01100  Metabolic pathways
Orthology
K00461  arachidonate 5-lipoxygenase [EC:1.13.11.34]
Other DBs
RHEA: 17964
LinkDB

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