KEGG   REACTION: R03815
Entry
R03815                      Reaction                               
Name
dihydrolipoylprotein:NAD+ oxidoreductase
Definition
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
Equation
Comment
a part step of glycine cleavage system (see R01221, R03425+R04125+R03815)
Reaction class
RC00001  C00003_C00004
RC00583  C02051_C02972
Enzyme
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00785  Lipoic acid metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
Module
M00621  Glycine cleavage system
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4
     R03815  Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.8.1.4
   R08550  [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine <=> Protein N6-(lipoyl)lysine
    R03815  Dihydrolipoylprotein <=> Lipoylprotein
Orthology
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Other DBs
RHEA: 15048
LinkDB

KEGG   REACTION: R07618
Entry
R07618                      Reaction                               
Name
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Definition
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
Equation
Comment
Oxo-acid dehydrogenase complexes, dihydrolipoyl dehydrogenase
Reaction class
RC00001  C00003_C00004
RC00583  C15972_C15973
Enzyme
Pathway
rn00010  Glycolysis / Gluconeogenesis
rn00020  Citrate cycle (TCA cycle)
rn00280  Valine, leucine and isoleucine degradation
rn00310  Lysine degradation
rn00620  Pyruvate metabolism
rn00640  Propanoate metabolism
rn00785  Lipoic acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4
     R07618  Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.8.1.4
   R08550  [Protein]-N6-[(R)-dihydrolipoyl]-L-lysine <=> Protein N6-(lipoyl)lysine
    R07618  Enzyme N6-(dihydrolipoyl)lysine <=> Enzyme N6-(lipoyl)lysine
Orthology
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Other DBs
RHEA: 15048
LinkDB

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