KEGG   REACTION: R04125
Entry
R04125                      Reaction                               
Name
[protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
Definition
[Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
Equation
C01242 + C00101 <=> C02972 + C00143 + C00014
Comment
a part step of glycine cleavage system (see R01221, R03425+R04125+R03815)
Reaction class
RC00022  C00101_C00143
RC00069  C01242_C02972
Enzyme
2.1.2.10
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00670  One carbon pool by folate
rn00785  Lipoic acid metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
Module
M00621  Glycine cleavage system
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.10
     R04125  [Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
Orthology
K00605  glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
Other DBs
RHEA: 16948
LinkDB

KEGG   RCLASS: RC00022
Entry
RC00022                     RClass                                 
Definition
N1b-N1y:*-C1x:C1b+C8y-C1x+C8y
N1x-N1y:*-C1x:C1y+C8y-C1y+C8y
Reactant pair
C00101_C00143
Related class
Reaction
R00945 R01221 R01225 R01226 R01669 R03704 R04125 R06613
R09093 R11955 R11956 R12548
Enzyme
1.4.1.27        2.1.1.74        2.1.1.148       2.1.2.1         
2.1.2.7         2.1.2.8         2.1.2.10        2.1.2.11        
2.1.5.1
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00670  One carbon pool by folate
rn00680  Methane metabolism
rn00785  Lipoic acid metabolism
rn01100  Metabolic pathways
rn01200  Carbon metabolism
rn01240  Biosynthesis of cofactors
Orthology
K00281  glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]
K00282  glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
K00283  glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
K00605  glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
K00606  3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
K02437  glycine cleavage system H protein
K03465  thymidylate synthase (FAD) [EC:2.1.1.148]
K19796  Straboviridae dCMP hydroxymethylase [EC:2.1.2.8]
K22578  sesamin methylene transferase [EC:2.1.5.1]

DBGET integrated database retrieval system