REACTION: R04125
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Entry
R04125 Reaction
Name
[protein]-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming)
Definition
[Protein]-S8-aminomethyldihydrolipoyllysine + Tetrahydrofolate <=> Dihydrolipoylprotein + 5,10-Methylenetetrahydrofolate + Ammonia
Equation
C01242
+
C00101
<=>
C02972
+
C00143
+
C00014
Comment
a part step of glycine cleavage system (see
R01221, R03425+R04125+R03815
)
Reaction class
RC00022
C00101_C00143
RC00069
C01242_C02972
Enzyme
2.1.2.10
Pathway
rn00260
Glycine, serine and threonine metabolism
rn00670
One carbon pool by folate
rn01100
Metabolic pathways
Orthology
K00605
aminomethyltransferase [EC:
2.1.2.10
]
Other DBs
RHEA:
16948
LinkDB
All DBs
RCLASS: RC00022
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Entry
RC00022 RClass
Definition
N1b-N1y:*-C1x:C1b+C8y-C1x+C8y
N1x-N1y:*-C1x:C1y+C8y-C1y+C8y
Reactant pair
C00101_C00143
Related class
DB search
Reaction
R00945
R01221
R01225
R01226
R01669
R03704
R04125
R06613
R09093
R11955
R11956
R12548
Enzyme
1.4.1.27
2.1.1.74
2.1.1.148
2.1.2.1
2.1.2.7
2.1.2.8
2.1.2.10
2.1.2.11
2.1.5.1
Pathway
rn00260
Glycine, serine and threonine metabolism
rn00670
One carbon pool by folate
rn00680
Methane metabolism
rn01100
Metabolic pathways
rn01200
Carbon metabolism
rn01240
Biosynthesis of cofactors
Orthology
K00281
glycine dehydrogenase [EC:
1.4.4.2
]
K00282
glycine dehydrogenase subunit 1 [EC:
1.4.4.2
]
K00283
glycine dehydrogenase subunit 2 [EC:
1.4.4.2
]
K00382
dihydrolipoamide dehydrogenase [EC:
1.8.1.4
]
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
K00605
aminomethyltransferase [EC:
2.1.2.10
]
K00606
3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:
2.1.2.11
]
K02437
glycine cleavage system H protein
K03465
thymidylate synthase (FAD) [EC:
2.1.1.148
]
K19796
Escherichia phage dCMP hydroxymethylase [EC:
2.1.2.8
]
K22578
sesamin methylene transferase [EC:
2.1.5.1
]
DBGET
integrated database retrieval system
