KEGG   REACTION: R05357
Entry
R05357                      Reaction                               
Name
amidinoproclavaminate amidinohydrolase
Definition
Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea
Equation
C06657 + C00001 <=> C06658 + C00086
Comment
pah gene
Reaction class
RC00024  C06657_C06658
RC00329  C00086_C06657
Enzyme
3.5.3.22
Pathway
rn00331  Clavulanic acid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.3  In linear amidines
    3.5.3.22
     R05357  Guanidinoproclavaminic acid + H2O <=> Proclavaminic acid + Urea
Orthology
K12676  proclavaminate amidinohydrolase [EC:3.5.3.22]
Reference
1  [PMID:9614345]
  Authors
McGowan SJ, Bycroft BW, Salmond GP.
  Title
Bacterial production of carbapenems and clavams: evolution of beta-lactam antibiotic pathways.
  Journal
Trends Microbiol 6:203-8 (1998)
DOI:10.1016/S0966-842X(98)01251-7
Other DBs
RHEA: 17004
LinkDB

KEGG   RCLASS: RC00024
Entry
RC00024                     RClass                                 
Definition
N1a-N1b:*-C2c:C1b-C1b
Reactant pair
C00037_C00581    C00062_C00077    C00077_C05933
C00099_C03065    C00134_C00179    C00179_C03047
C00245_C01959    C00315_C20560    C00334_C01035
C00515_C00792    C01110_C03771    C03296_C03415
C06657_C06658
Related class
Reaction
R00551 R00565 R00775 R00913 R01157 R01418 R01686 R01989
R01990 R02458 R03250 R03477 R04189 R05357 R05547 R10347
R10466 R12506 R13308
Enzyme
2.1.4.1         2.1.4.2         2.1.4.3         3.5.3.1         
3.5.3.2         3.5.3.7         3.5.3.10        3.5.3.11        
3.5.3.17        3.5.3.20        3.5.3.22        3.5.3.23        
3.5.3.24        3.5.3.25        3.5.3.27
Pathway
rn00220  Arginine biosynthesis
rn00260  Glycine, serine and threonine metabolism
rn00330  Arginine and proline metabolism
rn00331  Clavulanic acid biosynthesis
rn00430  Taurine and hypotaurine metabolism
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01230  Biosynthesis of amino acids
Orthology
K00613  glycine amidinotransferase [EC:2.1.4.1]
K01476  arginase [EC:3.5.3.1]
K01480  agmatinase [EC:3.5.3.11]
K01484  succinylarginine dihydrolase [EC:3.5.3.23]
K04340  scyllo-inosamine-4-phosphate amidinotransferase 1 [EC:2.1.4.2]
K12255  guanidinobutyrase [EC:3.5.3.7]
K12676  proclavaminate amidinohydrolase [EC:3.5.3.22]
K19723  Nomega-hydroxy-L-arginine amidinohydrolase [EC:3.5.3.25]
K25365  guanidinobutyrase / D-arginase [EC:3.5.3.7 3.5.3.10]
K27001  taurocyamine/4-guanidinobutanoate/3-guanidinopropanoate hydrolase [EC:3.5.3.- 3.5.3.7 3.5.3.17]
K27545  arginine dihydrolase [EC:3.5.3.27]
K27683  N1-aminopropylagmatine ureohydrolase [EC:3.5.3.24]

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