REACTION: R12948
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Entry
R12948 Reaction
Name
(8S)-8-amino-7-oxononanoate:[protein]-L-lysine aminotransferase (N-carboxylating)
Definition
(8S)-8-Amino-7-oxononanoate + Protein lysine + CO2 <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate
Equation
C22463
+
C02188
+
C00011
<=>
C22464
+
C03531
Comment
two-step reaction (see
R12949+R12950, R12952+R12953
)
Enzyme
2.6.1.121
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.121
R12948 (8S)-8-Amino-7-oxononanoate + Protein lysine + CO2 <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate
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REACTION: R12952
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Entry
R12952 Reaction
Definition
(8S)-8-Amino-7-oxononanoate + Protein lysine + NADH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NAD+
Equation
C22463
+
C02188
+
C00004
+
C00080
<=>
C22465
+
C00001
+
C00003
Comment
the first step of two-step reaction (see
R12948, R12952+R12953
)
NADPH (see
R12949
)
Enzyme
2.6.1.121
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.121
R12952 (8S)-8-Amino-7-oxononanoate + Protein lysine + NADH + H+ <=> [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NAD+
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REACTION: R12953
Help
Entry
R12953 Reaction
Definition
[Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NAD+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADH + H+
Equation
C22465
+
C00011
+
C00001
+
C00003
<=>
C22464
+
C03531
+
C00004
+
C00080
Comment
the second step of two-step reaction (see
R12948, R12952+R12953
)
NADPH (see
R12950
)
Enzyme
2.6.1.121
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.6 Transferring nitrogenous groups
2.6.1 Transaminases
2.6.1.121
R12953 [Protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + CO2 + H2O + NAD+ <=> (7R,8S)-8-Amino-7-(carboxyamino)nonanoate + [Protein]-(S)-2-amino-6-oxohexanoate + NADH + H+
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All DBs
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