KEGG   REACTION: R13220
Entry
R13220                      Reaction                               
Name
dihydrotestosterone:NADP+ 17-oxidoreductase
Definition
5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+
Equation
C00674 + C00005 + C00080 <=> C03917 + C00006
Reaction class
RC00127  C00674_C03917
Enzyme
1.1.1.51        1.1.1.64
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51
     R13220  5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+
    1.1.1.64
     R13220  5alpha-Androstane-3,17-dione + NADPH + H+ <=> Dihydrotestosterone + NADP+
Orthology
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K10207  testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
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