KEGG   PATHWAY: ath00290
Entry
ath00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Arabidopsis thaliana (thale cress)
Class
Metabolism; Amino acid metabolism
Pathway map
ath00290  Valine, leucine and isoleucine biosynthesis
ath00290

Module
ath_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ath00290]
ath_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ath00290]
ath_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ath00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT1G10060  BCAT-1; branched-chain amino acid transaminase 1 [KO:K00826] [EC:2.6.1.42]
AT1G10070  BCAT-2; branched-chain amino acid transaminase 2 [KO:K00826] [EC:2.6.1.42]
AT1G18500  MAML-4; methylthioalkylmalate synthase-like 4 [KO:K01649] [EC:2.3.3.13]
AT1G31180  IMD3; isopropylmalate dehydrogenase 3 [KO:K00052] [EC:1.1.1.85]
AT1G50090  BCAT7; D-aminoacid aminotransferase-like PLP-dependent enzymes superfamily protein [KO:K00826] [EC:2.6.1.42]
AT1G50110  [KO:K00826] [EC:2.6.1.42]
AT1G74040  IMS1; 2-isopropylmalate synthase 1 [KO:K01649] [EC:2.3.3.13]
AT1G80560  IMD2; isopropylmalate dehydrogenase 2 [KO:K00052] [EC:1.1.1.85]
AT2G31810  [KO:K01653] [EC:2.2.1.6]
AT2G43090  [KO:K01704] [EC:4.2.1.33 4.2.1.35]
AT2G43100  IPMI2; isopropylmalate isomerase 2 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
AT3G10050  OMR1; L-O-methylthreonine resistant 1 [KO:K01754] [EC:4.3.1.19]
AT3G23940  [KO:K01687] [EC:4.2.1.9]
AT3G48560  CSR1; chlorsulfuron/imidazolinone resistant 1 [KO:K01652] [EC:2.2.1.6]
AT3G49680  BCAT3; branched-chain aminotransferase 3 [KO:K00826] [EC:2.6.1.42]
AT3G58610  [KO:K00053] [EC:1.1.1.86]
AT3G58990  IPMI1; isopropylmalate isomerase 1 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
AT4G13430  IIL1; isopropyl malate isomerase large subunit 1 [KO:K01703] [EC:4.2.1.33 4.2.1.35]
AT5G14200  IMD1; isopropylmalate dehydrogenase 1 [KO:K21360] [EC:1.1.1.85 1.1.1.-]
AT5G16290  VAT1; VALINE-TOLERANT 1 [KO:K01653] [EC:2.2.1.6]
AT5G65780  ATBCAT-5; branched-chain amino acid aminotransferase 5 / branched-chain amino acid transaminase 5 (BCAT5) [KO:K00826] [EC:2.6.1.42]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
PMID:15292141
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
ath00260  Glycine, serine and threonine metabolism
ath00280  Valine, leucine and isoleucine degradation
ath00620  Pyruvate metabolism
KO pathway
ko00290   

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