KEGG   PATHWAY: bsia00290
Entry
bsia00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Bacillus siamensis
Class
Metabolism; Amino acid metabolism
Pathway map
bsia00290  Valine, leucine and isoleucine biosynthesis
bsia00290

Module
bsia_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bsia00290]
bsia_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bsia00290]
bsia_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bsia00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Bacillus siamensis [GN:bsia]
Gene
CWD84_11015  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
CWD84_06815  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
CWD84_06820  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
CWD84_06810  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
CWD84_02470  acetolactate synthase AlsS [KO:K01652] [EC:2.2.1.6]
CWD84_06790  ilvB; acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
CWD84_06795  ilvN; acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
CWD84_06800  ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
CWD84_10970  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
CWD84_01285  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
CWD84_20615  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
CWD84_09770  Glu/Leu/Phe/Val dehydrogenase [KO:K00263] [EC:1.4.1.9]
CWD84_06805  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
bsia00260  Glycine, serine and threonine metabolism
bsia00280  Valine, leucine and isoleucine degradation
bsia00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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