KEGG   PATHWAY: cpip00290
Entry
cpip00290                   Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Chryseobacterium piperi
Class
Metabolism; Amino acid metabolism
Pathway map
cpip00290  Valine, leucine and isoleucine biosynthesis
cpip00290

Module
cpip_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:cpip00290]
cpip_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:cpip00290]
cpip_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:cpip00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Chryseobacterium piperi [GN:cpip]
Gene
CJF12_05400  threonine dehydratase [KO:K01754] [EC:4.3.1.19]
CJF12_04840  leuC; 3-isopropylmalate dehydratase large subunit [KO:K01703] [EC:4.2.1.33 4.2.1.35]
CJF12_04835  leuD; 3-isopropylmalate dehydratase small subunit [KO:K01704] [EC:4.2.1.33 4.2.1.35]
CJF12_04830  leuB; 3-isopropylmalate dehydrogenase [KO:K00052] [EC:1.1.1.85]
CJF12_05415  ilvB; acetolactate synthase, large subunit, biosynthetic type [KO:K01652] [EC:2.2.1.6]
CJF12_05410  acetolactate synthase small subunit [KO:K01653] [EC:2.2.1.6]
CJF12_05405  ilvC; ketol-acid reductoisomerase [KO:K00053] [EC:1.1.1.86]
CJF12_05420  ilvD; dihydroxy-acid dehydratase [KO:K01687] [EC:4.2.1.9]
CJF12_05425  ilvE; branched-chain-amino-acid transaminase [KO:K00826] [EC:2.6.1.42]
CJF12_05880  branched-chain amino acid aminotransferase [KO:K00826] [EC:2.6.1.42]
CJF12_04845  2-isopropylmalate synthase [KO:K01649] [EC:2.3.3.13]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
cpip00260  Glycine, serine and threonine metabolism
cpip00280  Valine, leucine and isoleucine degradation
cpip00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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