Entry
Name
Phenylalanine metabolism - Dickeya aquatica
Class
Metabolism; Amino acid metabolism
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Organism
Dickeya aquatica [GN:
daq ]
Gene
DAQ1742_01234 dat; D-alanine aminotransferase. Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second-half reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components [KO:K00824 ] [EC:2.6.1.21 ]
Compound
C00596 2-Hydroxy-2,4-pentadienoate
C01198 3-(2-Hydroxyphenyl)propanoate
C01772 trans-2-Hydroxycinnamate
C02137 alpha-Oxo-benzeneacetic acid
C02763 2-Hydroxy-3-phenylpropenoate
C03519 N-Acetyl-L-phenylalanine
C03589 4-Hydroxy-2-oxopentanoate
C04044 3-(2,3-Dihydroxyphenyl)propanoate
C04479 2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
C06207 2,6-Dihydroxyphenylacetate
C11457 3-(3-Hydroxyphenyl)propanoic acid
C11588 cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol
C12621 trans-3-Hydroxycinnamate
C12622 cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
C12623 trans-2,3-Dihydroxycinnamate
C12624 2-Hydroxy-6-ketononatrienedioate
C14144 5-Carboxy-2-pentenoyl-CoA
C14145 (3S)-3-Hydroxyadipyl-CoA
C19945 3-Oxo-5,6-dehydrosuberyl-CoA
C19946 3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
C19975 2-Oxepin-2(3H)-ylideneacetyl-CoA
C20062 2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA
Reference
Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
Title
[Cellular Functions and Metabolic Maps] (In Japanese)
Journal
Tokyo Kagaku Dojin (1997)
Reference
Authors
Arai H, Yamamoto T, Ohishi T, Shimizu T, Nakata T, Kudo T.
Title
Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441.
Journal
Reference
Authors
Diaz E, Ferrandez A, Garcia JL.
Title
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
Journal
Reference
Authors
Ferrandez A, Garcia JL, Diaz E.
Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
Journal
Reference
Authors
Hwang JY, Park J, Seo JH, Cha M, Cho BK, Kim J, Kim BG
Title
Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.
Journal
Reference
Authors
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G
Title
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
Journal
Related pathway
daq00400 Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway
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