KEGG   PATHWAY: dme00740
Entry
dme00740                    Pathway                                
Name
Riboflavin metabolism - Drosophila melanogaster (fruit fly)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
dme00740  Riboflavin metabolism
dme00740

Other DBs
GO: 0006771
Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG16848  Flad2; flavin adenine dinucleotide synthetase 2 [KO:K00953] [EC:2.7.7.2]
Dmel_CG2846  Rfk; riboflavin kinase, isoform B [KO:K00861] [EC:2.7.1.26]
Dmel_CG31469  Argp; arginine phosphatase [KO:K14394] [EC:3.1.3.2 3.1.3.48]
Dmel_CG33747  [KO:K14394] [EC:3.1.3.2 3.1.3.48]
Dmel_CG33748  primo-1; primo-1, isoform B [KO:K14394] [EC:3.1.3.2 3.1.3.48]
Dmel_CG4407  Flad1; flavin adenine dinucleotide synthetase 1, isoform A [KO:K00953] [EC:2.7.7.2]
Dmel_CG6656  CG6656; uncharacterized protein [KO:K14410] [EC:3.1.3.2]
Dmel_CG7899  Acph-1; acid phosphatase 1, isoform A [KO:K14410] [EC:3.1.3.2]
Dmel_CG9471  CG9471; uncharacterized protein, isoform B [KO:K05901] [EC:1.3.1.24 1.5.1.30]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
dme00030  Pentose phosphate pathway
dme00040  Pentose and glucuronate interconversions
dme00230  Purine metabolism
dme00860  Porphyrin metabolism
dme00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   

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