Drosophila melanogaster (fruit fly): Dmel_CG7144
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Entry
Dmel_CG7144 CDS
T00030
Symbol
LKRSDH
Name
(RefSeq) lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform B
KO
K14157
alpha-aminoadipic semialdehyde synthase [EC:
1.5.1.8
1.5.1.9
]
Organism
dme
Drosophila melanogaster (fruit fly)
Pathway
dme00310
Lysine degradation
dme01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
dme00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
Dmel_CG7144 (LKRSDH)
Enzymes [BR:
dme01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
Dmel_CG7144 (LKRSDH)
1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming)
Dmel_CG7144 (LKRSDH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Sacchrp_dh_C
Sacchrp_dh_NADP
AlaDh_PNT_N
Shikimate_DH
AlaDh_PNT_C
F420_oxidored
NAD_binding_3
2-Hacid_dh_C
Motif
Other DBs
NCBI-GeneID:
34064
NCBI-ProteinID:
NP_001285719
FlyBase:
FBgn0286198
UniProt:
Q9VLX0
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Position
2L
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AA seq
928 aa
AA seq
DB search
MWRVIQLRATIAHPFTRQRHSRVIAIRREDQSVWERRAPFGPTHVQKLVKQNVKVIVQPS
NRRAYPMQAYMQAGAHIQEDISDASVIFGVKQVPIDALIPGKTYCFFSHTIKAQESNMPL
LDAILEKKIRLIDYERIIDERGARQVAFGKYAGVAGMVNILHGIGLRLLALGHHTPFMHI
GPAHNYRNSSMARQAIRDCGYEISLGMMPKSIGPLTFVFTGSGNVSQGAQEVFSELPIEY
VPPEMLRKVAEHGNQNKLYGCEVSRSDHLERREGGGFDAKEYDEFPERYISTFSTKIAPY
ASVIVNGIYWAVGSPKLISIPDAKNLLRPANTPWLPTSKGSPALPHRMLAICDISADPGG
SIEFMNECTTIDTPFCLYDADRNKDTKSFKGPGVLVCSIDNMPTQLPRESTDLFGELLAP
HVHDIIKSDAKKPLAEENFSYPIQSAIIASNGQLTEGFQYIQELRESQSHRSRHKMEGSS
ESDKKVLVLGAGMVSAPLVEWLHREKDVSITVCSQVKEEADRLAQQYAGVDSVYLDVNES
TGHLQELCGRADVVVSLLPYSLHGMVARYCVAEGTHMVTASYLNDEISGLHEEAKAKGVT
IMNEVGLDPGIDHLLALECIHEVQDKGAVVESFVSYCGGLPAPEHSNNALRYKFSWSPRG
VLLNTLSAAKYLSQGQIVEISGGGELMSSPRSLDFLPGFALEGFPNRDSTKYGNLYGLGR
DVHTLLRGTIRYKGFSESIKPMQLLGLIDPEPHALLHPSGPDVTWRQLVIHLMGMSDSTI
FYENLKQKLTERIGDVDGIESLGLLDDTPVVKLNTPLDTLSHYLSKRLAFERDERDLVVL
RHEVGIRWPDGRREERGINFVVYGQPQGHSAMAMTVGKPAAIAAKMILDGEIQERGVLLP
FTPDIYRPMLQRLRSEGLTATETSRWLN
NT seq
2787 nt
NT seq
+upstream
nt +downstream
nt
atgtggcgagtgattcaactgcgcgcaacaatcgcgcatccgttcaccagacaacgtcat
agtcgagtgattgccattcggcgagaggatcagtcggtgtgggagcgacgagctccgttt
ggaccaacccacgtccagaagttggtcaagcagaatgtcaaggtcatagtgcagccgtcc
aatcgtcgtgcctaccccatgcaggcctacatgcaggctggagctcatattcaggaggac
atcagtgatgcttcggtgatattcggagtgaaacaggtgcccatagatgcactgattcct
gggaagacctactgcttcttttcgcacacgattaaagcgcaggaatcaaatatgccgctt
ttggatgctattttggagaagaaaattcggctcatcgactatgagcgaatcatcgacgaa
cgcggagcacgacaggtggcctttggcaaatatgccggagtggctggcatggtgaacatc
ctgcacggcattggactgcgtcttttggccctgggacatcatacaccattcatgcacatt
ggacccgctcataactatcgcaattcctcgatggctcgccaggcaatccgggattgtggc
tacgagatctcgcttggcatgatgcccaagtccattggaccacttacatttgtgttcact
ggctctggaaatgtttcccaaggtgcccaggaggtgttctccgagctgcccattgagtat
gttccaccggagatgctacgcaaggtggccgaacatggaaatcaaaataagctttacggc
tgcgaggtgagccgatcggatcatctggagcgtcgtgagggcggcggatttgatgccaag
gaatacgatgagttccccgaacgatacatctccacctttagcacgaagatagctccgtac
gcatcggttattgttaacggcatctactgggccgtaggcagtcccaagttgatcagcatt
ccggatgccaagaatctgctacgtccggcaaacactccctggctgccgacgagcaagggt
agtccggctttgccacatcgcatgctggccatttgcgacatttccgctgatcccggtggc
tccattgagtttatgaacgagtgcaccaccatcgacactccattctgcttgtacgatgcg
gacaggaataaggataccaagagctttaagggacccggagttttagtctgttcgattgat
aatatgcctacacaattgcccagagaatcgacggatttgtttggagagctgttggctcct
catgttcatgatattataaagagcgatgccaagaagccgttggcagaggagaacttctca
taccccattcagtcggctattatcgccagcaacggtcagctgacggagggcttccagtat
attcaggagctccgagagtcgcaaagccacagatcgcgccacaagatggagggaagttcg
gagtctgacaagaaggtcttggttctgggagctggcatggtgtccgctccactcgtagag
tggcttcatcgcgaaaaggacgtcagcataacggtttgctcgcaggtcaaggaggaagcc
gatcgcctggctcagcagtatgctggagtggacagcgtctatctggatgtgaacgagagc
actggtcatctgcaggagctgtgcggcagggcagatgtagtagtttccctgctgccctac
agtctccatggcatggtggcacgttattgcgtggcagagggcacccacatggttaccgca
agttatctgaacgacgagatctccggtttgcacgaggaggccaaggccaagggtgtgacc
atcatgaacgaggtgggcttggatcctggtatcgatcaccttctggcactggagtgcatc
cacgaggtgcaggacaagggagcagttgtcgagtccttcgtgagctattgtggcggtctg
cctgcaccggagcattccaataatgccctaagatataagttctcttggtcacccagggga
gtacttctcaacacactttccgctgcaaaatatctgagtcagggacaaattgtggagatt
tctggaggtggggaactcatgtcaagtcctcgcagcttggatttcctgccaggattcgcc
ctggagggtttccccaacagggattccaccaaatacggcaacctttacggcttaggcagg
gatgtgcacactttgcttcgtggaaccatacgttataagggcttttcggaatcgattaag
cctatgcagctcttgggacttatcgatccggagccacatgcattgctacatcccagtggg
ccggatgtcacgtggcgccagctggtgatccatctaatgggcatgtcggactcgaccatc
ttctacgagaacctcaagcagaagctgactgagcgcattggagatgtggacggcatcgag
agcttgggtctgctggatgatactcctgtggtgaagctcaacactccgctggatacgctt
agtcactatctctcgaagagacttgccttcgagcgggatgaacgcgacctggtggtgctg
cgccatgaagttggcatccgttggcccgatggtcgtcgtgaggagcgtggaatcaatttt
gtggtctacggacagccccagggtcactccgccatggcgatgactgtgggcaagccggct
gccatcgcagccaaaatgatcctagacggtgagatccaggaacgcggcgtcctgctgccc
ttcactcccgacatttatcgtcccatgctgcaacgtctgcgctccgagggtctgactgcc
acggaaacctccagatggctaaattaa
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