KEGG   DRUG: ロラゼパム
エントリ  
D00365                      Drug                                   
一般名   
ロラゼパム (JP18);
Lorazepam (JP18/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (A-S Medication Solutions), LORAZEPAM (ATLANTIC BIOLOGICALS CORP.), LORAZEPAM (ATLANTIC BIOLOGICALS CORP.), LORAZEPAM (Actavis Pharma), LORAZEPAM (Akorn), LORAZEPAM (Akorn), LORAZEPAM (American Health Packaging), LORAZEPAM (American Health Packaging), LORAZEPAM (Amneal Pharmaceuticals LLC), LORAZEPAM (Amneal Pharmaceuticals LLC), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aphena Pharma Solutions - Tennessee), LORAZEPAM (Aurolife Pharma), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Bryant Ranch Prepack), LORAZEPAM (Cardinal Health 107), LORAZEPAM (Clinical Solutions Wholesale), LORAZEPAM (DIRECT RX), LORAZEPAM (DirectRX), LORAZEPAM (DirectRx), LORAZEPAM (Direct_Rx), LORAZEPAM (Hospira), LORAZEPAM (Hospira), LORAZEPAM (Hospira), LORAZEPAM (International Medication Systems), LORAZEPAM (Leading Pharma), LORAZEPAM (Major Pharmaceuticals), LORAZEPAM (Medsource Pharmaceuticals), LORAZEPAM (NCS HealthCare of KY), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (NuCare Pharmaceuticals), LORAZEPAM (PD-Rx Pharmaceuticals), LORAZEPAM (PD-Rx Pharmaceuticals), LORAZEPAM (PD-Rx Pharmaceuticals), LORAZEPAM (PD-Rx Pharmaceuticals), LORAZEPAM (PD-Rx Pharmaceuticals), LORAZEPAM (PharmPak), LORAZEPAM (PharmPak), LORAZEPAM (Pharmaceutical Associates), LORAZEPAM (Preferred Pharmaceuticals), LORAZEPAM (Preferred Pharmaceuticals), LORAZEPAM (Preferred Pharmaceuticals), LORAZEPAM (Proficient Rx LP), LORAZEPAM (Proficient Rx LP), LORAZEPAM (Proficient Rx LP), LORAZEPAM (Proficient Rx LP), LORAZEPAM (Proficient Rx LP), LORAZEPAM (Quality Care Products), LORAZEPAM (Quality Care Products), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (REMEDYREPACK), LORAZEPAM (RPK Pharmaceuticals), LORAZEPAM (RPK Pharmaceuticals), LORAZEPAM (RPK Pharmaceuticals), LORAZEPAM (RedPharm Drug), LORAZEPAM (RedPharm Drug), LORAZEPAM (RedPharm Drug), LORAZEPAM (RedPharm Drug), LORAZEPAM (St. Mary's Medical Park Pharmacy), LORAZEPAM (Teva Pharmaceuticals USA), LORAZEPAM (West-Ward Pharmaceuticals Corp.)
組成式   
C15H10Cl2N2O2
質量    
320.0119
分子量   
321.1581
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01567  GABA-A受容体作動薬
 DG01914  ベンゾジアゼピン系抗不安薬
 DG03199  抗てんかん薬
代謝酵素基質薬
 DG02924  UGT基質薬
  DG03190  UGT2B7基質薬
  DG03187  UGT2B15基質薬
コード   
薬効分類: 1124 1139
ATCコード: N05BA06
商品: D00365<JP/US>
効能    
抗不安薬, 抗けいれん薬, マイナートランキライザー
  疾患
神経症における不安 [DS:H01662]
コメント  
ベンゾジアゼピン誘導体
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: UGT2B7 [HSA:7364], UGT2B15 [HSA:7366]
相互作用  

構造マップ 
map07030  抗不安薬
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   112  催眠鎮静剤、抗不安剤
    1124  ベンゾジアゼピン系製剤
     D00365  ロラゼパム (JP18)
   113  抗てんかん剤
    1139  その他の抗てんかん剤
     D00365  ロラゼパム (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05B 抗不安薬
    N05BA ベンゾジアゼピン誘導体
     N05BA06 ロラゼパム
      D00365  ロラゼパム (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗けいれん薬
  ガンマアミノ酪酸(GABA)増強剤
   ベンゾジアゼピン
    ロラゼパム
     D00365  ロラゼパム (JP18)
 抗不安薬
  ベンゾジアゼピン
   ロラゼパム
    D00365  ロラゼパム (JP18)
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01567  GABA-A受容体作動薬
   D00365  ロラゼパム
  DG01914  ベンゾジアゼピン系抗不安薬
   D00365  ロラゼパム
  DG03199  抗てんかん薬
   D00365  ロラゼパム
 代謝酵素基質薬
  DG02924  UGT基質薬
   DG03190  UGT2B7基質薬
    D00365  ロラゼパム
   DG03187  UGT2B15基質薬
    D00365  ロラゼパム
ターゲットに基づく医薬品分類 [BR:jp08310]
 イオンチャネル
  リガンド依存性イオンチャネル
   GABA (イオンチャネル型)
    GABR
     D00365  ロラゼパム (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00365  ロラゼパム
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00365
リンク   
CAS: 846-49-1
PubChem: 7847431
LigandBox: D00365
日化辞: J3.337E
LinkDB    

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