KEGG   DRUG: クロニジン塩酸塩
エントリ  
D00604                      Drug                                   
一般名   
クロニジン塩酸塩 (JP18);
Clonidine hydrochloride (JP18/USP)
商品名   
米国の商品 
  後発品
CLONIDINE (Ingenus Pharmaceuticals), CLONIDINE (XGen Pharmaceuticals DJB), CLONIDINE HCI (HF Acquisition Co LLC), CLONIDINE HYDROCHLORIDE (A-S Medication Solutions), CLONIDINE HYDROCHLORIDE (Actavis Pharma), CLONIDINE HYDROCHLORIDE (Actavis Pharma), CLONIDINE HYDROCHLORIDE (Ajanta Pharma USA), CLONIDINE HYDROCHLORIDE (Alembic Pharmaceuticals), CLONIDINE HYDROCHLORIDE (American Health Packaging), CLONIDINE HYDROCHLORIDE (American Health Packaging), CLONIDINE HYDROCHLORIDE (Amneal Pharmaceuticals NY LLC), CLONIDINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CLONIDINE HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), CLONIDINE HYDROCHLORIDE (Asclemed USA), CLONIDINE HYDROCHLORIDE (Asclemed USA), CLONIDINE HYDROCHLORIDE (Aurobindo Pharma Limited), CLONIDINE HYDROCHLORIDE (AvKARE), CLONIDINE HYDROCHLORIDE (BluePoint Laboratories), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Bryant Ranch Prepack), CLONIDINE HYDROCHLORIDE (Cardinal Health 107), CLONIDINE HYDROCHLORIDE (Clinical Solutions Wholesale), CLONIDINE HYDROCHLORIDE (Denton Pharma), CLONIDINE HYDROCHLORIDE (Denton Pharma), CLONIDINE HYDROCHLORIDE (Denton Pharma), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (DirectRX), CLONIDINE HYDROCHLORIDE (Golden State Medical Supply), CLONIDINE HYDROCHLORIDE (Hikma Pharmaceuticals USA), CLONIDINE HYDROCHLORIDE (Lupin Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Method Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (NCS HealthCare of KY), CLONIDINE HYDROCHLORIDE (Northwind Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (NuCare Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (PD-Rx Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Par Pharmaceutical), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Preferred Pharmaceuticals), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Proficient Rx LP), CLONIDINE HYDROCHLORIDE (Quality Care Products), CLONIDINE HYDROCHLORIDE (Quality Care Products), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (REMEDYREPACK), CLONIDINE HYDROCHLORIDE (RedPharm Drug), CLONIDINE HYDROCHLORIDE (RedPharm Drug), CLONIDINE HYDROCHLORIDE (Solco Healthcare LLC), CLONIDINE HYDROCHLORIDE (Solco Healthcare LLC), CLONIDINE HYDROCHLORIDE (St. Mary's Medical Park Pharmacy), CLONIDINE HYDROCHLORIDE (TruPharma), CLONIDINE HYDROCHLORIDE (Unichem Pharmaceuticals (USA)), CLONIDINE HYDROCHLORIDE (Xiamen LP Pharmaceutical), CLONIDINE HYDROCHLORIDE (Zydus Lifesciences Limited), CLONIDINE HYDROCHLORIDE (Zydus Pharmaceuticals USA), CLONIDINE HYDROCHLORIDE (medsource pharmaceuticals)
組成式   
C9H9Cl2N3. HCl
質量    
264.994
分子量   
266.5548
構造式   
Simcomp   
クラス   
心血管系用薬
 DG01738  中枢性交感神経抑制薬
 DG01456  アドレナリン受容体作動薬
  DG01450  α-アドレナリン受容体作動薬
   DG01449  α2-アドレナリン受容体作動薬
 DG03231  血圧降下薬
コード   
薬効分類: 2149
ATCコード: C02AC01 N02CX02 S01EA04
化学構造グループ: DG00249
商品 (DG00249): D00281<US> D00604<JP/US>
効能    
血圧降下薬, α2アドレナリン受容体作動薬
  疾患
高血圧症 [DS:H01633]
コメント  
イミダゾリン誘導体
ターゲット 
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  パスウェイ
hsa04022  cGMP-PKG シグナル伝達経路
hsa04080  神経刺激性リガンドとレセプターの相互作用
相互作用  

構造マップ 
map07215  α-アドレナリン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   214  血圧降下剤
    2149  その他の血圧降下剤
     D00604  クロニジン塩酸塩 (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C02 降圧薬
   C02A 交感神経抑制薬、中枢作用型
    C02AC イミダゾリン受容体作動薬
     C02AC01 クロニジン
      D00604  クロニジン塩酸塩 (JP18) <JP/US>
 N 神経系
  N02 鎮痛薬
   N02C 抗片頭痛製剤
    N02CX その他の抗片頭痛製剤
     N02CX02 クロニジン
      D00604  クロニジン塩酸塩 (JP18) <JP/US>
 S 感覚器
  S01 眼科用薬
   S01E 抗緑内障製剤と縮瞳薬
    S01EA 緑内障治療用交感神経刺激薬
     S01EA04 クロニジン
      D00604  クロニジン塩酸塩 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗悪性腫瘍薬
  抗悪性腫瘍補助剤・緩和剤
   クロニジン
    D00604  クロニジン塩酸塩 (JP18)
 心血管治療薬
  アルファアドレナリン作動薬
   クロニジン
    D00604  クロニジン塩酸塩 (JP18)
 中枢神経系用薬
  注意欠陥多動性障害治療薬, 非アンフェタミン
   クロニジン
    D00604  クロニジン塩酸塩 (JP18)
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG01738  中枢性交感神経抑制薬
   DG00249  クロニジン
    D00604  クロニジン塩酸塩
  DG01456  アドレナリン受容体作動薬
   DG01450  α-アドレナリン受容体作動薬
    DG01449  α2-アドレナリン受容体作動薬
     DG00249  クロニジン
      D00604  クロニジン塩酸塩
  DG03231  血圧降下薬
   DG00249  クロニジン
    D00604  クロニジン塩酸塩
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG03231  血圧降下薬 [商品一覧]
   D00604  クロニジン塩酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   アドレナリン
    ADRA2
     D00604  クロニジン塩酸塩 (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00604  クロニジン塩酸塩
医薬品グループ [BR:jp08330]
 心血管系用薬
  DG01738  中枢性交感神経抑制薬
   DG00249  クロニジン
  DG01456  アドレナリン受容体作動薬
   DG01450  α-アドレナリン受容体作動薬
    DG01449  α2-アドレナリン受容体作動薬
     DG00249  クロニジン
  DG03231  血圧降下薬
   DG00249  クロニジン
リンク   
CAS: 4205-91-8
PubChem: 7847670
LigandBox: D00604
日化辞: J237.323H
LinkDB    

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