KEGG   DRUG: 塩酸ミダゾラム
エントリ  
D00696                      Drug                                   

一般名   
塩酸ミダゾラム;
Midazolam hydrochloride (USAN)
米国の商品 
  後発品
MIDAZOLAM (General Injectables and Vaccines), MIDAZOLAM (A-S Medication Solutions), MIDAZOLAM (Almaject), MIDAZOLAM (Almaject), MIDAZOLAM (Civica), MIDAZOLAM (General Injectables and Vaccines), MIDAZOLAM (General Injectables and Vaccines), MIDAZOLAM (General Injectables and Vaccines), MIDAZOLAM (General Injectables and Vaccines), MIDAZOLAM (West-Ward Pharmaceuticals Corp.), MIDAZOLAM (West-Ward Pharmaceuticals Corp.), MIDAZOLAM (West-Ward Pharmaceuticals Corp.), MIDAZOLAM (A-S Medication Solutions), MIDAZOLAM HYDROCHLORIDE (A-S Medication Solutions), MIDAZOLAM HYDROCHLORIDE (A-S Medication Solutions), MIDAZOLAM HYDROCHLORIDE (ATLANTIC BIOLOGICALS CORP.), MIDAZOLAM HYDROCHLORIDE (ATLANTIC BIOLOGICALS CORP.), MIDAZOLAM (Akorn), MIDAZOLAM (Alvogen), MIDAZOLAM (Alvogen), MIDAZOLAM HYDROCHLORIDE (American Health Packaging), MIDAZOLAM (Athenex Pharmaceutical Division), MIDAZOLAM (Athenex Pharmaceutical Division), MIDAZOLAM HYDROCHLORIDE (Bryant Ranch Prepack), MIDAZOLAM HYDROCHLORIDE (Cardinal Health), MIDAZOLAM (Fresenius Kabi USA), MIDAZOLAM (Fresenius Kabi USA), MIDAZOLAM (Fresenius Kabi USA), MIDAZOLAM HYDROCHLORIDE (General Injectables & Vaccines), MIDAZOLAM (General Injectables & Vaccines), MIDAZOLAM HYDROCHLORIDE (Gland Pharma Limited), MIDAZOLAM HYDROCHLORIDE (Gland Pharma Limited), MIDAZOLAM HYDROCHLORIDE (Heritage Pharmaceuticals Inc d/b/a as Avet Pharmaceuticals), MIDAZOLAM HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), MIDAZOLAM HYDROCHLORIDE (Hospira), MIDAZOLAM HYDROCHLORIDE (Hospira), MIDAZOLAM HYDROCHLORIDE (Hospira), MIDAZOLAM HYDROCHLORIDE (Major Pharmaceuticals), MIDAZOLAM HYDROCHLORIDE (Major Pharmaceuticals), MIDAZOLAM HYDROCHLORIDE (Paddock Laboratories), MIDAZOLAM HYDROCHLORIDE (Precision Dose), MIDAZOLAM HYDROCHLORIDE (Precision Dose), MIDAZOLAM HYDROCHLORIDE (West-Ward Pharmaceuticals Corp.)
組成式   
C18H13ClFN3. HCl
質量    
361.0549
分子量   
362.2283
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01835  ベンゾジアゼピン系催眠鎮静薬
 DG01567  GABA-A受容体作動薬
代謝酵素基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
コード   
ATCコード: N05CD08
化学構造グループ: DG00920
商品 (DG00920): D00550<JP/US> D00696<US>
効能    
静脈麻酔薬, 催眠鎮静薬
コメント  
ベンゾジアゼピン誘導体
ターゲット 
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04727  GABA作動性シナプス
代謝    
Enzyme: CYP3A4 [HSA:1576]
相互作用  

構造マップ 
map07032  催眠薬
map07230  GABA-A受容体の作動薬と拮抗薬
階層分類  
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05C 睡眠薬と鎮静薬
    N05CD ベンゾジアゼピン誘導体
     N05CD08 ミダゾラム
      D00696  塩酸ミダゾラム <US>
ターゲットに基づく医薬品分類 [BR:jp08310]
 イオンチャネル
  リガンド依存性イオンチャネル
   GABA (イオンチャネル型)
    GABR
     D00696  塩酸ミダゾラム <US>
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00696
リンク   
CAS: 59467-96-8
PubChem: 7847761
ChEBI: 6932
ChEMBL: CHEMBL1200420
DrugBank: DB00683
LigandBox: D00696
日化辞: J300.613A
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