KEGG PATHWAY: elc00564

PATHWAY: elc00564

Entry

elc00564                    Pathway

Name

Glycerophospholipid metabolism - Escherichia coli clone D i14

Class

Metabolism; Lipid metabolism

Pathway map

elc00564

Glycerophospholipid metabolism

Module

elc_M00093

Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:elc00564]

Other DBs

GO:

0006650

Organism

Escherichia coli clone D i14 [GN:elc]

Gene

i14_4094

gpsA; NAD(P)H-dependent glycerol-3-phosphate [KO:K00057] [EC:1.1.1.94]

i14_2581

glpA; sn-glycerol-3-phosphate dehydrogenase subunit A [KO:K00111] [EC:1.1.5.3]

i14_3875

glpD; glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]

i14_2582

glpB; anaerobic glycerol-3-phosphate dehydrogenase [KO:K00112] [EC:1.1.5.3]

i14_2583

glpC; sn-glycerol-3-phosphate dehydrogenase subunit C [KO:K00113]

i14_4596

plsB; glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]

i14_3504

ygiH; putative glycerol-3-phosphate acyltransferase [KO:K08591] [EC:2.3.1.275]

i14_3450

plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]

i14_4598

dgkA; diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]

i14_4336

pldA; phospholipase A [KO:K01058] [EC:3.1.1.32 3.1.1.4]

i14_4341

pldB; lysophospholipase L2 [KO:K01048] [EC:3.1.1.5]

i14_2579

glpQ; glycerophosphodiester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

i14_3908

ugpQ; cytoplasmic glycerophosphodiester [KO:K01126] [EC:3.1.4.46]

i14_3152

aas; bifunctional acyl carrier protein [KO:K05939] [EC:2.3.1.40 6.2.1.20]

i14_2773

eutA; reactivating factor for ethanolamine ammonia [KO:K04019]

i14_2772

eutB; ethanolamine ammonia-lyase heavy chain [KO:K03735] [EC:4.3.1.7]

i14_2771

eutC; ethanolamine ammonia-lyase small subunit [KO:K03736] [EC:4.3.1.7]

i14_4463

cdh; CDP-diacylglycerol pyrophosphatase [KO:K01521] [EC:3.6.1.26]

i14_1660

ynbB; hypothetical protein [KO:K00981] [EC:2.7.7.41]

i14_0195

cdsA; CDP-diglyceride synthase [KO:K00981] [EC:2.7.7.41]

i14_2906

pssA; phosphatidylserine synthase [KO:K00998] [EC:2.7.8.8]

i14_4755

psd; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]

i14_2141

pgsA; phosphatidylglycerophosphate synthetase [KO:K00995] [EC:2.7.8.5]

i14_0510

pgpA; phosphatidylglycerophosphatase A [KO:K01095] [EC:3.1.3.27]

i14_1577

pgpB; phosphatidylglycerophosphatase B [KO:K01096] [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]

i14_2878

yfhB; hypothetical protein [KO:K18697] [EC:3.1.3.27]

i14_0838

ybhO; cardiolipin synthase 2 [KO:K06131] [EC:2.7.8.-]

i14_1546

cls; cardiolipin synthetase [KO:K06131] [EC:2.7.8.-]

i14_1196

ymdC; hypothetical protein [KO:K06132] [EC:2.7.8.-]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

elc00010