Entry
Name
ABC transporters - Enterobacter quasiroggenkampii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Other DBs
Organism
Enterobacter quasiroggenkampii [GN:
equ ]
Gene
OM418_01265 malE; maltose/maltodextrin ABC transporter substrate-binding protein MalE [KO:K10108 ]
OM418_01270 malK; maltose/maltodextrin ABC transporter ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
OM418_01345 livJ; branched chain amino acid ABC transporter substrate-binding protein LivJ [KO:K01999 ]
OM418_01355 livK; high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK [KO:K01999 ]
OM418_01360 livH; high-affinity branched-chain amino acid ABC transporter permease LivH [KO:K01997 ]
OM418_01365 livM; branched chain amino acid ABC transporter permease LivM [KO:K01998 ]
OM418_01370 livG; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG [KO:K01995 ]
OM418_01375 livF; high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF [KO:K01996 ]
OM418_01380 ugpB; sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB [KO:K05813 ]
OM418_02295 ytfQ; galactofuranose ABC transporter substrate-binding protein YtfQ [KO:K23508 ]
OM418_03470 thiP; thiamine/thiamine pyrophosphate ABC transporter permease ThiP [KO:K02063 ]
OM418_03870 fhuD; Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD [KO:K23227 ]
OM418_03900 btuF; vitamin B12 ABC transporter substrate-binding protein BtuF [KO:K06858 ]
OM418_04085 metQ; methionine ABC transporter substrate-binding lipoprotein MetQ [KO:K02073 ]
OM418_05430 glnH; glutamine ABC transporter substrate-binding protein GlnH [KO:K10036 ]
OM418_05620 fepB; Fe2+-enterobactin ABC transporter substrate-binding protein [KO:K23185 ]
OM418_06590 glnH; glutamine ABC transporter substrate-binding protein GlnH [KO:K10036 ]
OM418_06740 gsiB; glutathione ABC transporter substrate-binding protein GsiB [KO:K13889 ]
OM418_06895 potF; spermidine/putrescine ABC transporter substrate-binding protein PotF [KO:K11073 ]
OM418_07135 macB; macrolide ABC transporter ATP-binding protein/permease MacB [KO:K05685 ] [EC:7.6.2.-]
OM418_07165 cydC; cysteine/glutathione ABC transporter ATP-binding protein/permease CydC [KO:K16012 ]
OM418_07170 cydD; cysteine/glutathione ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
OM418_08370 lolC; lipoprotein-releasing ABC transporter permease subunit LolC [KO:K09808 ]
OM418_08375 lolD; lipoprotein-releasing ABC transporter ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
OM418_08380 lolE; lipoprotein-releasing ABC transporter permease subunit LolE [KO:K09808 ]
OM418_08405 potD; spermidine/putrescine ABC transporter substrate-binding protein PotD [KO:K11069 ]
OM418_09820 osmX; osmoprotectant ABC transporter substrate-binding protein OsmX [KO:K05845 ]
OM418_12500 oppF; murein tripeptide/oligopeptide ABC transporter ATP-binding protein OppF [KO:K10823 ]
OM418_12520 oppA; oligopeptide ABC transporter substrate-binding protein OppA [KO:K15580 ]
OM418_13590 araF; arabinose ABC transporter substrate-binding protein AraF [KO:K10537 ]
OM418_13650 livM; high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998 ]
OM418_14770 mglC; galactose/methyl galactoside ABC transporter permease MglC [KO:K10541 ]
OM418_14780 mglB; galactose/glucose ABC transporter substrate-binding protein MglB [KO:K10540 ]
OM418_15465 hisJ; histidine ABC transporter substrate-binding protein HisJ [KO:K10014 ]
OM418_15470 argT; lysine/arginine/ornithine ABC transporter substrate-binding protein ArgT [KO:K10013 ]
OM418_17095 proW; glycine betaine/L-proline ABC transporter permease ProW [KO:K02001 ]
OM418_17100 proX; glycine betaine/L-proline ABC transporter substrate-binding protein ProX [KO:K02002 ]
OM418_19225 lsrB; autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555 ]
OM418_19735 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
OM418_19740 mlaE; lipid asymmetry maintenance ABC transporter permease subunit MlaE [KO:K02066 ]
OM418_22205 pstS; phosphate ABC transporter substrate-binding protein PstS [KO:K02040 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway