KEGG PATHWAY: hie00564

PATHWAY: hie00564

Entry

hie00564                    Pathway

Name

Glycerophospholipid metabolism - Haemophilus influenzae R2846 (nontypeable)

Class

Metabolism; Lipid metabolism

Pathway map

hie00564

Glycerophospholipid metabolism

Module

hie_M00093

Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:hie00564]

Other DBs

GO:

0006650

Organism

Haemophilus influenzae R2846 (nontypeable) [GN:hie]

Gene

R2846_0391

gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]

R2846_1652

glpA; Anaerobic glycerol-3-phosphate dehydrogenase subunit A [KO:K00111] [EC:1.1.5.3]

R2846_1653

glpB; Anaerobic glycerol-3-phosphate dehydrogenase subunit B [KO:K00112] [EC:1.1.5.3]

R2846_1654

glpC; Anaerobic glycerol-3-phosphate dehydrogenase subunit C [KO:K00113]

R2846_1578

plsB; glycerol-3-phosphate acyltransferase [KO:K00631] [EC:2.3.1.15]

R2846_0319

plsY; Probable glycerol-3-phosphate acyltransferase [KO:K08591] [EC:2.3.1.275]

R2846_1592

plsC; 1-acyl-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]

R2846_0242

dgkA; Diacylglycerol kinase [KO:K00901] [EC:2.7.1.107]

R2846_1691

pldB; Putative lysophospholipase L2 [KO:K01048] [EC:3.1.1.5]

R2846_1648

glpQ; Glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

R2846_1398

cdsA; CDP-diglyceride synthetase [KO:K00981] [EC:2.7.7.41]

R2846_0155

pssA; Phosphatidylserine synthase [KO:K00998] [EC:2.7.8.8]

R2846_0477

psd; Phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]

R2846_0513

pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]

R2846_0979

pgpA; Phosphatidylglycerophosphatase A [KO:K01095] [EC:3.1.3.27]

R2846_0428

pgpB; Putative phosphatidylglycerophosphatase B [KO:K01096] [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

hie00010