Homo sapiens (human): 1022
Help
Entry
1022 CDS
T01001
Symbol
CDK7, CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Name
(RefSeq) cyclin dependent kinase 7
KO
K02202
cyclin-dependent kinase 7 [EC:
2.7.11.22
2.7.11.23
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03022
Basal transcription factors
hsa03420
Nucleotide excision repair
hsa04110
Cell cycle
Network
nt06502
Nucleotide excision repair
Element
N01425
Global genome NER
N01430
Transcription-coupled NER
Drug target
Alvocidib (
DG02041
):
D02880
D09868
Zotiraciclib (
DG03058
):
D11599
D11600
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03022 Basal transcription factors
1022 (CDK7)
09124 Replication and repair
03420 Nucleotide excision repair
1022 (CDK7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
1022 (CDK7)
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
hsa03021
]
1022 (CDK7)
03019 Messenger RNA biogenesis [BR:
hsa03019
]
1022 (CDK7)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
1022 (CDK7)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.22 cyclin-dependent kinase
1022 (CDK7)
2.7.11.23 [RNA-polymerase]-subunit kinase
1022 (CDK7)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CMGC group
CDK family
1022 (CDK7)
Transcription machinery [BR:
hsa03021
]
Eukaryotic type
RNA polymerase II system
Basal transcription factors
TFIIH
1022 (CDK7)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA processing factors
5' end processing
Capping factors
1022 (CDK7)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
TFIIH complex
1022 (CDK7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Seadorna_VP7
Haspin_kinase
APH
FTA2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
1022
NCBI-ProteinID:
NP_001790
OMIM:
601955
HGNC:
1778
Ensembl:
ENSG00000134058
UniProt:
P50613
A0A0S2Z3F9
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:69234795..69277430
Genome browser
AA seq
346 aa
AA seq
DB search
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atggctctggacgtgaagtctcgggcaaagcgttatgagaagctggacttccttggggag
ggacagtttgccaccgtttacaaggccagagataagaacaccaaccaaattgtcgccatt
aagaaaatcaaacttggacatagatcagaagctaaagatggtataaatagaaccgcctta
agagagataaaattattacaggagctaagtcatccaaatataattggtctccttgatgct
tttggacataaatctaatattagccttgtctttgattttatggaaactgatctagaggtt
ataataaaggataatagtcttgtgctgacaccatcacacatcaaagcctacatgttgatg
actcttcaaggattagaatatttacatcaacattggatcctacatagggatctgaaacca
aacaacttgttgctagatgaaaatggagttctaaaactggcagattttggcctggccaaa
tcttttgggagccccaatagagcttatacacatcaggttgtaaccaggtggtatcgggcc
cccgagttactatttggagctaggatgtatggtgtaggtgtggacatgtgggctgttggc
tgtatattagcagagttacttctaagggttccttttttgccaggagattcagaccttgat
cagctaacaagaatatttgaaactttgggcacaccaactgaggaacagtggccggacatg
tgtagtcttccagattatgtgacatttaagagtttccctggaatacctttgcatcacatc
ttcagtgcagcaggagacgacttactagatctcatacaaggcttattcttatttaatcca
tgtgctcgaattacggccacacaggcactgaaaatgaagtatttcagtaatcggccaggg
ccaacacctggatgtcagctgccaagaccaaactgtccagtggaaaccttaaaggagcaa
tcaaatccagctttggcaataaaaaggaaaagaacagaggccttagaacaaggaggattg
cccaagaaactaattttttaa
DBGET
integrated database retrieval system
