KEGG    Network variation - Nucleotide excision repair
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ENTRYnt06502
NameNucleotide excision repair
CategoryPathway view; Replication and repair
Pathwayhsa03420 Nucleotide excision repair
DiseaseH00403 Disorders of nucleotide excision repair
Display drug-target relation   disease type
N01425    (CRL4+DDB2)=(XPC+RAD23A,RAD23B..(XPC+CETN2)=(ERCC3+ERCC2)=(GTF2H)=(CAK)
    White-Kernohan syndrome DDB1*
    XPE DDB2*
    XPC   XPC*
    XPB/CS/TTD2       ERCC3*
    XPD/TTD1/COFS2       ERCC2*
    TTD3         GTF2H5*
N01430    (POLR2+UVSSA)=(ERCC6+ERCC8+CRL4)(POLR2+UVSSA+ERCC6..=(ERCC3+ERCC2)=(GTF2H)=(CAK)
    NEDHIB POLR2A*
    UVSS3 UVSSA*
    CSB/UVSS1/COFS1   ERCC6*
    CSA/UVSS2   ERCC8*
N01431    (ERCC3+ERCC2+GTF2H..=ERCC5=XPA=RPA(ERCC1+ERCC4)=XPA=RPA=ERCC5PCNA=POLD,POLE,POLK,POL..LIG1,(LIG3+XRCC1)
    XPG/CS/COFS3   ERCC5*
    XPA     XPA*
    PFBMFT       RPA1*
    XPF/CS/FANCQ         ERCC4*
    COFS4         ERCC1*
    ATLD                 PCNA*
    IMD122                   POLD3*
    XPV                   POLH*

Disease nameDisease category
White-Kernohan syndromeH02560White-Kernohan syndromeCongenital malformation
XPEH01428Xeroderma pigmentosumCongenital malformation
XPCH01428Xeroderma pigmentosumCongenital malformation
XPB/CS/TTD2H01428Xeroderma pigmentosumCongenital malformation
H00076Cockayne syndromeNeurodegenerative disease
H00866TrichothiodystrophySkin disease
XPD/TTD1/COFS2H01428Xeroderma pigmentosumCongenital malformation
H00866TrichothiodystrophySkin disease
H02570Cerebro-oculo-facio-skeletal syndromeCongenital malformation
TTD3H00866TrichothiodystrophySkin disease
NEDHIBH02571Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalitiesNervous system disease
UVSS3H02131UV-sensitive syndromeSkin disease
CSB/UVSS1/COFS1H00076Cockayne syndromeNeurodegenerative disease
H02131UV-sensitive syndromeSkin disease
H02570Cerebro-oculo-facio-skeletal syndromeCongenital malformation
CSA/UVSS2H00076Cockayne syndromeNeurodegenerative disease
H02131UV-sensitive syndromeSkin disease
XPG/CS/COFS3H01428Xeroderma pigmentosumCongenital malformation
H00076Cockayne syndromeNeurodegenerative disease
H02570Cerebro-oculo-facio-skeletal syndromeCongenital malformation
XPAH01428Xeroderma pigmentosumCongenital malformation
PFBMFTH02569Pulmonary fibrosis and/or bone marrow failure, telomere-relatedHematologic disease
XPF/CS/FANCQH01428Xeroderma pigmentosumCongenital malformation
H00076Cockayne syndromeNeurodegenerative disease
H00238Fanconi anemiaHematologic disease
COFS4H02570Cerebro-oculo-facio-skeletal syndromeCongenital malformation
ATLDH02014Ataxia-telangiectasia-like syndromeImmune system disease
IMD122H00091T-B+Severe combined immunodeficiencyPrimary immunodeficiency
XPVH01428Xeroderma pigmentosumCongenital malformation