KEGG   Homo sapiens (human): 103910
Entry
103910            CDS       T01001                                 
Symbol
MYL12B, MLC-B, MRLC2
Name
(RefSeq) myosin light chain 12B
  KO
K12757  myosin regulatory light chain 12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103910 (MYL12B)
   04520 Adherens junction
    103910 (MYL12B)
   04530 Tight junction
    103910 (MYL12B)
  09142 Cell motility
   04814 Motor proteins
    103910 (MYL12B)
   04810 Regulation of actin cytoskeleton
    103910 (MYL12B)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103910 (MYL12B)
   04670 Leukocyte transendothelial migration
    103910 (MYL12B)
  09158 Development and regeneration
   04360 Axon guidance
    103910 (MYL12B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103910 (MYL12B)
   05131 Shigellosis
    103910 (MYL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    103910 (MYL12B)
   04147 Exosome [BR:hsa04147]
    103910 (MYL12B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     103910 (MYL12B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   103910 (MYL12B)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_11 EF-hand_5 EF-hand_9 DUF2666 DUF3741 SPARC_Ca_bdg 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 103910
NCBI-ProteinID: NP_001138416
OMIM: 609211
HGNC: 29827
Ensembl: ENSG00000118680
UniProt: O14950
LinkDB
Position
18:3262133..3278461
AA seq 172 aa
MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
LGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE
DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
NT seq 519 nt   +upstreamnt  +downstreamnt
atgtcgagcaaaaaggcaaagaccaagaccaccaagaagcgccctcagcgtgcaacatcc
aatgtgtttgccatgtttgaccagtcacagattcaggagttcaaagaggccttcaacatg
attgatcagaacagagatggcttcatcgacaaggaagatttgcatgatatgcttgcttct
ctagggaagaatcccactgatgcataccttgatgccatgatgaatgaggccccagggccc
atcaatttcaccatgttcctgaccatgtttggtgagaagttaaatggcacagatcctgaa
gatgtcatcagaaacgcctttgcttgctttgatgaagaagcaacaggcaccattcaggaa
gattacctaagagagctgctgacaaccatgggggatcggtttacagatgaggaagtggat
gagctgtacagagaagcacctattgacaaaaaggggaatttcaattacatcgagttcaca
cgcatcctgaaacatggagccaaagacaaagatgactga

KEGG   Homo sapiens (human): 10398
Entry
10398             CDS       T01001                                 
Symbol
MYL9, LC20, MLC-2C, MLC2, MMIHS4, MRLC1, MYRL2
Name
(RefSeq) myosin light chain 9
  KO
K12755  myosin regulatory light chain 9
Organism
hsa  Homo sapiens (human)
Pathway
hsa04022  cGMP-PKG signaling pathway
hsa04024  cAMP signaling pathway
hsa04270  Vascular smooth muscle contraction
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa04921  Oxytocin signaling pathway
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Disease
H01869  Megacystis microcolon intestinal hypoperistalsis syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    10398 (MYL9)
   04022 cGMP-PKG signaling pathway
    10398 (MYL9)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    10398 (MYL9)
   04520 Adherens junction
    10398 (MYL9)
   04530 Tight junction
    10398 (MYL9)
  09142 Cell motility
   04814 Motor proteins
    10398 (MYL9)
   04810 Regulation of actin cytoskeleton
    10398 (MYL9)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    10398 (MYL9)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    10398 (MYL9)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    10398 (MYL9)
  09158 Development and regeneration
   04360 Axon guidance
    10398 (MYL9)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    10398 (MYL9)
   05131 Shigellosis
    10398 (MYL9)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10398 (MYL9)
   04147 Exosome [BR:hsa04147]
    10398 (MYL9)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     10398 (MYL9)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   10398 (MYL9)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_5 EF-hand_11 GPHH DUF3741 SPARC_Ca_bdg
Other DBs
NCBI-GeneID: 10398
NCBI-ProteinID: NP_006088
OMIM: 609905
HGNC: 15754
Ensembl: ENSG00000101335
UniProt: P24844 A0A384NY64
LinkDB
Position
20:36541519..36551447
AA seq 172 aa
MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
LGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHE
DHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD
NT seq 519 nt   +upstreamnt  +downstreamnt
atgtccagcaagcgggccaaagccaagaccaccaagaagcggccacagcgggccacatcc
aatgtcttcgcaatgtttgaccagtcccagatccaggagtttaaggaggctttcaacatg
attgaccagaaccgtgatggcttcattgacaaggaggacctgcacgacatgctggcctcg
ctggggaagaaccccacagacgaatacctggagggcatgatgagcgaggccccggggccc
atcaacttcaccatgttcctcaccatgtttggggagaagctgaacggcacggaccccgag
gatgtgattcgcaacgcctttgcctgcttcgacgaggaagcctcaggtttcatccatgag
gaccacctccgggagctgctcaccaccatgggtgaccgcttcacagatgaggaagtggac
gagatgtaccgggaggcacccattgataagaaaggcaacttcaactacgtggagttcacc
cgcatcctcaaacatggcgccaaggataaagacgactag

KEGG   Homo sapiens (human): 10627
Entry
10627             CDS       T01001                                 
Symbol
MYL12A, HEL-S-24, MLC-2B, MLCB, MRCL3, MRLC3, MYL2B
Name
(RefSeq) myosin light chain 12A
  KO
K12757  myosin regulatory light chain 12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    10627 (MYL12A)
   04520 Adherens junction
    10627 (MYL12A)
   04530 Tight junction
    10627 (MYL12A)
  09142 Cell motility
   04814 Motor proteins
    10627 (MYL12A)
   04810 Regulation of actin cytoskeleton
    10627 (MYL12A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    10627 (MYL12A)
   04670 Leukocyte transendothelial migration
    10627 (MYL12A)
  09158 Development and regeneration
   04360 Axon guidance
    10627 (MYL12A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    10627 (MYL12A)
   05131 Shigellosis
    10627 (MYL12A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10627 (MYL12A)
   04147 Exosome [BR:hsa04147]
    10627 (MYL12A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     10627 (MYL12A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   10627 (MYL12A)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_11 EF-hand_5 EF-hand_9 DUF3741 DUF2666 SPARC_Ca_bdg
Other DBs
NCBI-GeneID: 10627
NCBI-ProteinID: NP_001289976
HGNC: 16701
Ensembl: ENSG00000101608
UniProt: P19105
LinkDB
Position
18:3247482..3256237
AA seq 171 aa
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL
GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED
YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
NT seq 516 nt   +upstreamnt  +downstreamnt
atgtcgagcaaaagaacaaagaccaagaccaagaagcgccctcagcgtgcaacatccaat
gtgtttgctatgtttgaccagtcacagattcaggagttcaaagaggccttcaacatgatt
gatcagaacagagatggtttcatcgacaaggaagatttgcatgatatgcttgcttcattg
gggaagaatccaactgatgagtatctagatgccatgatgaatgaggctccaggccccatc
aatttcaccatgttcctcaccatgtttggtgagaagttaaatggcacagatcctgaagat
gtcatcagaaatgcctttgcttgctttgatgaagaagcaactggcaccatacaggaagat
tacttgagagagctgctgacaaccatgggggatcggtttacagatgaggaagtggatgag
ctgtacagagaagcacctattgataaaaaggggaatttcaattacatcgagttcacacgc
atcctgaaacatggagccaaagacaaagatgactga

KEGG   Homo sapiens (human): 29895
Entry
29895             CDS       T01001                                 
Symbol
MYL11, DA1C, HUMMLC2B, MLC2B, MRLC2, MYLPF
Name
(RefSeq) myosin light chain 11
  KO
K12758  fast skeletal myosin light chain 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Disease
H00811  Distal arthrogryposis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    29895 (MYL11)
   04520 Adherens junction
    29895 (MYL11)
  09142 Cell motility
   04814 Motor proteins
    29895 (MYL11)
   04810 Regulation of actin cytoskeleton
    29895 (MYL11)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    29895 (MYL11)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    29895 (MYL11)
   05131 Shigellosis
    29895 (MYL11)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    29895 (MYL11)
   04147 Exosome [BR:hsa04147]
    29895 (MYL11)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     29895 (MYL11)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   29895 (MYL11)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_5
Other DBs
NCBI-GeneID: 29895
NCBI-ProteinID: NP_001311387
OMIM: 617378
HGNC: 29824
Ensembl: ENSG00000180209
UniProt: Q96A32
LinkDB
Position
16:30370934..30377991
AA seq 169 aa
MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRL
NVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFL
EELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQE
NT seq 510 nt   +upstreamnt  +downstreamnt
atggcacccaagagggccaagagaaggacagtagagggcggaagctccagcgtcttctcc
atgttcgaccagactcagatccaggagttcaaagaggccttcactgtgatcgaccagaac
cgtgatggtattatagacaaggaggaccttcgggacaccttcgcagccatgggccgcctc
aatgtgaagaatgaggagttggatgccatgatgaaggaagccagcggtcccatcaacttc
accgtcttcctgaccatgttcggggagaagctcaagggtgccgaccctgaggatgtgatc
accggagccttcaaggtcttggaccctgagggaaagggcaccatcaagaagaagttcctg
gaggagctgctgaccacgcagtgtgaccgcttctcccaggaggagatcaagaacatgtgg
gcggccttcccccccgacgtgggcggcaacgtcgactacaaaaacatctgctacgtcatc
acgcacggcgacgccaaggaccaggagtag

KEGG   Homo sapiens (human): 4633
Entry
4633              CDS       T01001                                 
Symbol
MYL2, CMH10, MFM12, MLC-2, MLC-2s/v, MLC-2v, MLC2
Name
(RefSeq) myosin light chain 2
  KO
K10351  myosin regulatory light chain 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04371  Apelin signaling pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05410  Hypertrophic cardiomyopathy
hsa05414  Dilated cardiomyopathy
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Disease
H00292  Hypertrophic cardiomyopathy
H00595  Myofibrillar myopathies
Drug target
Aficamten: D12253
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    4633 (MYL2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4633 (MYL2)
   04520 Adherens junction
    4633 (MYL2)
   04530 Tight junction
    4633 (MYL2)
  09142 Cell motility
   04814 Motor proteins
    4633 (MYL2)
   04810 Regulation of actin cytoskeleton
    4633 (MYL2)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    4633 (MYL2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    4633 (MYL2)
   04261 Adrenergic signaling in cardiomyocytes
    4633 (MYL2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    4633 (MYL2)
   05131 Shigellosis
    4633 (MYL2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    4633 (MYL2)
   05414 Dilated cardiomyopathy
    4633 (MYL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4633 (MYL2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     4633 (MYL2)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 EF-hand_5
Other DBs
NCBI-GeneID: 4633
NCBI-ProteinID: NP_000423
OMIM: 160781
HGNC: 7583
Ensembl: ENSG00000111245
UniProt: P10916 Q6IB42
Structure
LinkDB
Position
12:complement(110910845..110921449)
AA seq 166 aa
MAPKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVN
VKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVR
EMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
NT seq 501 nt   +upstreamnt  +downstreamnt
atggcacctaagaaagcaaagaagagagccgggggcgccaactccaacgtgttctccatg
ttcgaacagacccaaatccaggaatttaaggaggccttcactatcatggaccagaacagg
gatggcttcattgacaagaacgatctgagagacacctttgctgcccttgggcgagtgaac
gtgaaaaatgaagaaattgatgaaatgatcaaggaggctccgggtccaattaactttact
gtgttcctcacaatgtttggggagaaacttaagggagcggaccctgaggaaaccattctc
aacgcattcaaagtgtttgaccctgaaggcaaaggggtgctgaaggctgattacgttcgg
gaaatgctgaccacgcaggcggagaggttttccaaggaggaggttgaccagatgttcgcc
gccttcccccctgacgtgactggcaacttggactacaagaacctggtgcacatcatcacc
cacggagaagagaaggactag

KEGG   Homo sapiens (human): 4636
Entry
4636              CDS       T01001                                 
Symbol
MYL5, MYLC2
Name
(RefSeq) myosin light chain 5
  KO
K12753  myosin regulatory light chain 5
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    4636 (MYL5)
   04520 Adherens junction
    4636 (MYL5)
  09142 Cell motility
   04814 Motor proteins
    4636 (MYL5)
   04810 Regulation of actin cytoskeleton
    4636 (MYL5)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    4636 (MYL5)
  09158 Development and regeneration
   04360 Axon guidance
    4636 (MYL5)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    4636 (MYL5)
   05131 Shigellosis
    4636 (MYL5)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4636 (MYL5)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     4636 (MYL5)
SSDB
Motif
Pfam: EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Lipoprotein_6 Caleosin SPARC_Ca_bdg
Other DBs
NCBI-GeneID: 4636
NCBI-ProteinID: NP_002468
OMIM: 160782
HGNC: 7586
Ensembl: ENSG00000215375
UniProt: Q02045
LinkDB
Position
4:674542..682028
AA seq 173 aa
MASRKTKKKEGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDTYA
SLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKGKI
NKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
NT seq 522 nt   +upstreamnt  +downstreamnt
atggccagcaggaagaccaagaagaaggaagggggtgccctccgggcccagagagcctca
tccaatgtcttctccaactttgagcagactcagatccaggagttcaaggaggcattcaca
ctcatggatcagaaccgagatggcttcattgacaaggaggacctgaaggacacctatgcc
tccctgggcaagaccaacgtcaaggacgacgagctggacgccatgctcaaagaggcctcg
gggcccatcaacttcaccatgtttctgaacctgtttggggagaagctgagcggtaccgac
gccgaggagaccattcttaacgccttcaagatgctggacccggacgggaaagggaaaatc
aacaaggagtacatcaagcgtctgctgatgtcccaggctgacaagatgacggcggaagag
gtggaccagatgttccagttcgcctccatcgatgtggcgggcaacctggactacaaggcg
ctcagctacgtgatcacccacggggaggagaaggaggagtga

KEGG   Homo sapiens (human): 58498
Entry
58498             CDS       T01001                                 
Symbol
MYL7, MYL2A, MYLC2A
Name
(RefSeq) myosin light chain 7
  KO
K12754  myosin regulatory light chain 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    58498 (MYL7)
   04520 Adherens junction
    58498 (MYL7)
  09142 Cell motility
   04814 Motor proteins
    58498 (MYL7)
   04810 Regulation of actin cytoskeleton
    58498 (MYL7)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    58498 (MYL7)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    58498 (MYL7)
   05131 Shigellosis
    58498 (MYL7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    58498 (MYL7)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     58498 (MYL7)
SSDB
Motif
Pfam: EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_7 EF-hand_5 CHCH EF-hand_9
Other DBs
NCBI-GeneID: 58498
NCBI-ProteinID: NP_067046
OMIM: 613993
HGNC: 21719
Ensembl: ENSG00000106631
UniProt: Q01449
LinkDB
Position
7:complement(44138864..44141332)
AA seq 175 aa
MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
NT seq 528 nt   +upstreamnt  +downstreamnt
atggccagcaggaaggcggggacccggggcaaggtggcagccaccaagcaggcccaacgt
ggttcttccaacgtcttttccatgtttgaacaagcccagatacaggagttcaaagaagcc
ttcagctgtatcgaccagaatcgtgatggcatcatctgcaaggcagacctgagggagacc
tactcccagctggggaaggtgagtgtcccagaggaggagctggacgccatgctgcaagag
ggcaagggccccatcaacttcaccgtcttcctcacgctctttggggagaagctcaatggg
acagaccccgaggaagccatcctgagtgccttccgcatgtttgaccccagcggcaaaggg
gtggtgaacaaggatgagttcaagcagcttctcctgacccaggcagacaagttctctcca
gctgaggtggagcagatgttcgccctgacacccatggacctggcggggaacatcgactac
aagtcactgtgctacatcatcacccatggagacgagaaagaggaatga

KEGG   Homo sapiens (human): 93408
Entry
93408             CDS       T01001                                 
Symbol
MYL10, MYLC2PL, PLRLC
Name
(RefSeq) myosin light chain 10
  KO
K12756  myosin regulatory light chain 10
Organism
hsa  Homo sapiens (human)
Pathway
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06135  Cytoskeletal regulation (viruses and bacteria)
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    93408 (MYL10)
   04520 Adherens junction
    93408 (MYL10)
  09142 Cell motility
   04814 Motor proteins
    93408 (MYL10)
   04810 Regulation of actin cytoskeleton
    93408 (MYL10)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    93408 (MYL10)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    93408 (MYL10)
   05131 Shigellosis
    93408 (MYL10)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    93408 (MYL10)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     93408 (MYL10)
SSDB
Motif
Pfam: EF-hand_6 EF-hand_7 EF-hand_8 EF-hand_1 EF-hand_5 TC1
Other DBs
NCBI-GeneID: 93408
NCBI-ProteinID: NP_612412
OMIM: 617177
HGNC: 29825
Ensembl: ENSG00000106436
UniProt: Q9BUA6
LinkDB
Position
7:complement(101613330..101629296)
AA seq 226 aa
MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA
LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN
VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK
EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD
NT seq 681 nt   +upstreamnt  +downstreamnt
atgttgcttaggctggtctcaaactcctggcctcaagtgatcctccctcctcggcctccc
aaagtgctgggattacaggcaccgagaagagctcggaaaagagcagaaggcaccgccagc
tccaacgtcttctccatgtttgatcagtcccagatccaggagtttaaagagagtctggct
ctgtcgcccaggctggagcgcaatggcatgatctcggctcactgcaacctctgcctcacg
ggttcaagcaattctcctgcctcagcctcccaagctttcaccatcatggaccagaaccgt
gatggcttcatcgacaaagaggacttgagggacacctttgccgcgctgggccgcatcaat
gtcaagaacgaggaactggaggccatggtgaaggaggcccccggacccatcaacttcacg
gtgttcctgaccatgtttggggagaagctgaagggcacggacccagaggagaccattctc
cacgccttcaaagtgttcgacactgaagggaaaggtttcgtcaaggccgatgtcatcaaa
gaaaaacttatgacccaggcagaccgcttcagtgaggaggaggtcaagcagatgtttgca
gcatttcccccagatgtgtgcggcaacctggactacagaaacctgtgctacgtcatcact
cacggtgaagagaaggattag

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