Homo sapiens (human): 10411
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Entry
10411 CDS
T01001
Symbol
RAPGEF3, CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910
Name
(RefSeq) Rap guanine nucleotide exchange factor 3
KO
K08014
Rap guanine nucleotide exchange factor 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04015
Rap1 signaling pathway
hsa04024
cAMP signaling pathway
hsa04072
Phospholipase D signaling pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04670
Leukocyte transendothelial migration
hsa04720
Long-term potentiation
hsa04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
10411 (RAPGEF3)
04072 Phospholipase D signaling pathway
10411 (RAPGEF3)
04024 cAMP signaling pathway
10411 (RAPGEF3)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
10411 (RAPGEF3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
10411 (RAPGEF3)
09156 Nervous system
04726 Serotonergic synapse
10411 (RAPGEF3)
04720 Long-term potentiation
10411 (RAPGEF3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
cNMP_binding
RasGEF_N
DEP
Motif
Other DBs
NCBI-GeneID:
10411
NCBI-ProteinID:
NP_001092002
OMIM:
606057
HGNC:
16629
Ensembl:
ENSG00000079337
UniProt:
O95398
Q99777
Structure
PDB
LinkDB
All DBs
Position
12:complement(47734363..47758880)
Genome browser
AA seq
881 aa
AA seq
DB search
MVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGR
QLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDE
GALCHVKHDWAFQDRDAQFYRFPGPEPEPVGTHEMEEELAEAVALLSQRGPDALLTVALR
KPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTS
WYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDF
NRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLE
AMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKR
QQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLEN
GCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASV
REVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELI
PHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTA
NLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLS
NSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDM
TFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARI
STCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
NT seq
2646 nt
NT seq
+upstream
nt +downstream
nt
atggtgttgagaaggatgcaccggccccgaagctgctcctaccagctgctgctggagcac
cagcgtccgagctgcatccaggggctgcgctggacaccactcaccaacagcgaggagtcc
ctggatttcagcgagagcctggagcaggcctccacagagcgggtgctcagggctgggagg
cagctgcatcggcatctgctggccacctgcccaaacctcatccgagaccggaagtaccac
cttaggctctatcggcagtgctgctctggccgggagctggtggatgggatcttggccctg
ggacttggggtccattcccggagccaagttgtgggaatctgccaggtgctgctggatgaa
ggtgccctctgccatgtgaaacacgactgggccttccaggaccgagatgcccaattctac
cggttccccgggcccgagcccgagcccgtgggaactcatgagatggaggaggagttggcc
gaagctgtggccctgctctcccagcgggggcctgacgccctgctcactgtggcacttcga
aagcccccaggtcagcgcacggatgaagagctggacctcatctttgaggagctgctgcac
atcaaggctgtggcccacctctccaactcggtgaagcgagaattagcggctgttctgctc
tttgaaccacacagcaaggcagggaccgtgttgttcagccagggggacaagggcacttcg
tggtacattatctggaagggatctgtcaacgtggtgacccatggcaaggggctggtgacc
accctgcatgagggagatgattttggacagctggctctggtgaatgatgcaccccgggca
gccaccatcatcctgcgagaagacaactgtcatttcctgcgtgtggacaagcaggacttc
aaccgtatcatcaaggatgtggaggcaaagaccatgcggctggaagaacatggcaaagtg
gtgctggtgctggagagagcctctcagggcgccggcccttcccgacccccaaccccaggc
aggaaccggtatacagtgatgtctggcaccccagagaagatcctagagcttctgttggag
gccatgggaccagattccagtgctcatgacccaacagagacattcctcagcgacttcctc
ctgacccacagggtcttcatgcccagcgcccaactctgcgctgcccttctgcaccacttc
catgtggagcctgcgggtggcagcgagcaggagcgcagcacctacgtctgcaacaagagg
cagcagatcttgcggctggtcagccagtgggtggccctgtatggctccatgctccacact
gaccctgtggccaccagcttcctccagaaactctcagacctggtgggcagggacacccga
ctcagcaacctgctgagggagcagtggccagagaggcggcgatgccacaggttggagaat
ggctgtgggaatgcatctcctcagatgaaggcccggaacttgcctgtttggctccccaac
caggacgagccccttcctggcagcagctgtgccatccaagttggggataaagtcccctat
gacatctgccggccagaccactcagtgttgaccctgcagctgcctgtgacagcctccgtg
agagaggtgatggcagcgttggcccaggaggatggctggaccaaggggcaggtgctggtg
aaggtcaattctgcaggtgatgccattggcctgcagccagatgcccgtggtgtggccaca
tctctggggctcaatgagcgtctctttgttgtcaacccacaggaagtgcatgagctgatc
ccacaccctgaccagctggggcccactgtgggctctgctgaggggctggacctggtgagt
gccaaggacctggcaggccagctgacggaccacgactggagcctcttcaacagtatccac
caggtggagctgatccactatgtgctgggcccccagcatctgcgggatgtcaccaccgcc
aacctggagcgcttcatgcgccgcttcaatgagctgcagtactgggtggccaccgagctg
tgtctctgccccgtgcccggcccccgggcccagctgctcaggaagttcattaagctggcg
gcccacctcaaggagcagaagaatctcaattccttctttgccgtcatgtttggcctcagc
aactcggccatcagccgcctagcccacacctgggagcggctgcctcacaaagtccggaag
ctgtactccgccctcgagaggctgctggatccctcatggaaccaccgggtataccgactg
gccctcgccaagctctcccctcctgtcatccccttcatgccccttcttctcaaagacatg
accttcattcatgagggaaaccacacactagtggagaatctcatcaactttgagaagatg
agaatgatggccagagccgcgcggatgctgcaccactgccgaagccacaaccctgtgcct
ctctcaccactcagaagccgagtttcccacctccacgaggacagccaggtggcgaggatt
tccacatgctcggagcagtccctgagcacccggagtccagccagcacctgggcttatgtc
cagcagctgaaggtcattgacaaccagcgggaactctcccgcctctcccgagagctggag
ccatga
Homo sapiens (human): 11069
Help
Entry
11069 CDS
T01001
Symbol
RAPGEF4, CAMP-GEFII, CGEF2, EPAC, EPAC_2, EPAC2, Nbla00496
Name
(RefSeq) Rap guanine nucleotide exchange factor 4
KO
K04351
Rap guanine nucleotide exchange factor 4
Organism
hsa
Homo sapiens (human)
Pathway
hsa04015
Rap1 signaling pathway
hsa04024
cAMP signaling pathway
hsa04072
Phospholipase D signaling pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04670
Leukocyte transendothelial migration
hsa04911
Insulin secretion
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
11069 (RAPGEF4)
04072 Phospholipase D signaling pathway
11069 (RAPGEF4)
04024 cAMP signaling pathway
11069 (RAPGEF4)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
11069 (RAPGEF4)
09152 Endocrine system
04911 Insulin secretion
11069 (RAPGEF4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
11069 (RAPGEF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
11069 (RAPGEF4)
Membrane trafficking [BR:
hsa04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
Rab associated proteins
11069 (RAPGEF4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
cNMP_binding
DEP
RasGEF_N
RA_2
Motif
Other DBs
NCBI-GeneID:
11069
NCBI-ProteinID:
NP_008954
OMIM:
606058
HGNC:
16626
Ensembl:
ENSG00000091428
UniProt:
Q8WZA2
LinkDB
All DBs
Position
2:172735318..173052893
Genome browser
AA seq
1011 aa
AA seq
DB search
MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGY
YENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDN
TPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENT
PLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTE
LVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLP
TEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHL
STTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD
FGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKV
PAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVF
MPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMA
FLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQK
RQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEK
VVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQM
TIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKR
VQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLM
DPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTART
VRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP
NT seq
3036 nt
NT seq
+upstream
nt +downstream
nt
atggtcgctgcgcacgctgcccattcttcctcctctgccgagtggatcgcctgcctggat
aaaagaccactggagcgatccagcgaagatgtggatataatcttcactcgactgaaagaa
gttaaagcttttgagaaatttcacccaaatctccttcatcagatttgcttatgtggttat
tatgagaatctggaaaagggaataacattatttcgccagggtgatattggaacaaactgg
tatgctgtcctggcagggtctttggatgttaaagtatctgagaccagcagtcaccaggat
gctgtgaccatctgtaccctgggaattgggacggcctttggagagtccattctggacaac
acaccccgccatgcaaccatcgttaccagggagagcagtgaactgctccgcatcgagcag
aaggacttcaaggcactatgggagaaatatcgacagtatatggcaggacttctggctcct
ccttatggtgttatggaaacgggctctaacaatgacaggattcctgacaaggagaacaca
cctctcattgaacctcacgttcctcttcgtcctgctaacaccattaccaaggtcccttca
gagaagatcctcagagctggaaaaattttacgaaatgccattctctctcgagcacctcac
atgataagagatagaaaataccacctaaagacatacagacaatgctgtgtgggaactgaa
ctggtggactggatgatgcagcagacaccatgtgttcactcccggactcaagctgttggc
atgtggcaagtcctgttagaagatggtgttctcaaccacgtggaccaggagcaccatttc
caagacaaatatttattctatcgatttctggatgatgagcacgaggatgcccctttgcct
actgaggaggagaagaaggagtgtgatgaggagctccaggacaccatgctgctgctgtca
cagatgggccccgacgcccacatgaggatgatccttcgcaaaccacctggccagaggact
gtggatgacctagagattatctatgaggagcttcttcatattaaagccttatcccatctt
tctaccacagtgaaacgagagttagcaggtgttctcatttttgagtctcacgccaaagga
gggactgtgttgtttaaccagggggaagaaggtacctcctggtacattattctaaaagga
tcagtgaatgtagtcatttacggcaagggtgtggtctgcaccctgcatgaaggagatgac
ttcggcaagttagcactagtgaatgatgccccacgagctgcctctatcgtcttacgagaa
gataactgccatttcttaagagtagacaaggaggatttcaaccggatcctaagggacgtg
gaggcgaatacagtcagacttaaagaacatgaccaagatgtcttggtgctggagaaggtc
ccagcagggaacagagcttctaatcaaggaaactcacagcctcagcaaaagtatactgtg
atgtcaggaacacctgaaaaaattttagagcattttctagaaacaatacgccttgaggca
actttaaatgaagcaacagattctgttttaaatgactttattatgatgcactgtgttttt
atgccaaatacccagctttgcccggcactggtggcccactaccacgcacagccttcacaa
ggtacagaacaggagaaaatggattatgccctcaacaataagaggcgagtcatccgcctg
gttctacagtgggctgccatgtatggagacctcctgcaagaggatgacgtgtctatggcc
ttcctggaggagttttatgtatctgtatcagatgatgcccggatgattgctgccctcaag
gagcaactgccagagttggagaagattgtcaagcaaatctcagaagatgcaaaggcacca
caaaagaagcacaaggttcttttgcaacagttcaatacgggcgatgagagagcccagaag
cgccagcctatccgcggctctgatgaagttctgtttaaggtctattgcatggaccacacc
tacacaaccattcgggtgccagtggccacttcggtgaaggaagtcatcagtgcagttgcc
gacaagctgggctccggggagggcctgatcatagtcaagatgagttccggaggagaaaag
gtggtgctcaaacctaatgatgtttcagtatttacgacgctcaccattaatggacgcctg
tttgcttgcccgcgagagcaattcgattcactgactcccttaccagaacaggaaggccca
actgttggaacagtgggaacttttgaactgatgagctccaaagatttagcataccagatg
acaatttatgattgggaactcttcaactgcgtgcatgagctggagctaatctatcacaca
tttggaaggcataattttaaaaagaccacagcaaacttggatttgttcctgaggagattt
aatgaaattcagttttgggtcgtcactgagatctgcctttgttctcagctcagcaagcgt
gttcagctattaaaaaaatttattaagatagcagcccactgtaaggagtataaaaatctg
aattccttttttgccatcgtcatgggactaagtaacgttgctgtgagccgcttggcacta
acgtgggagaaactgccaagcaagttcaagaagttctatgcggagtttgaaagtttaatg
gacccttcaaggaaccacagggcctacaggctgacagtagctaagctggaacctcctctc
atccccttcatgcctttgctcattaaagatatgacatttactcatgaggggaacaagacg
ttcattgacaatctagtaaactttgaaaaaatgcgcatgattgcaaatacggccagaaca
gtgagatactacaggagccaacccttcaatcctgatgcagctcaagctaataagaaccat
caggatgtccggagttatgtacggcaattaaatgtgattgacaaccagagaactttatca
cagatgtcacacagattagagcctcgtcgaccatag
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integrated database retrieval system
