Homo sapiens (human): 10594
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Entry
10594 CDS
T01001
Symbol
PRPF8, HPRP8, PRP8, PRPC8, RP13, SNRNP220
Name
(RefSeq) pre-mRNA processing factor 8
KO
K12856
pre-mRNA-processing factor 8
Organism
hsa
Homo sapiens (human)
Pathway
hsa03040
Spliceosome
Disease
H00527
Retinitis pigmentosa
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
10594 (PRPF8)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03041 Spliceosome [BR:
hsa03041
]
10594 (PRPF8)
Spliceosome [BR:
hsa03041
]
Complex B
U4/U6.U5 tri-snRNP components
U5 snRNP specific factors
10594 (PRPF8)
Complex C
U5 SnRNP specific factors
10594 (PRPF8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PROCN
PRP8_domainIV
U6-snRNA_bdg
PRO8NT
U5_2-snRNA_bdg
PROCT
RRM_4
JAB
Motif
Other DBs
NCBI-GeneID:
10594
NCBI-ProteinID:
NP_006436
OMIM:
607300
HGNC:
17340
Ensembl:
ENSG00000174231
UniProt:
Q6P2Q9
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(1650629..1684867)
Genome browser
AA seq
2335 aa
AA seq
DB search
MAGVFPYRGPGNPVPGPLAPLPDYMSEEKLQEKARKWQQLQAKRYAEKRKFGFVDAQKED
MPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLY
HITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYAD
NILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYR
LANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDIN
KIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKTEDPDLPAFYFDPLINPIS
HRHSVKSQEPLPDDDEEFELPEFVEPFLKDTPLYTDNTANGIALLWAPRPFNLRSGRTRR
ALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATK
FFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRF
GNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMR
QIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQF
EGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCW
KANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLT
RLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLI
LALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMD
LYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGIN
NLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYK
DMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATE
AAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARM
RLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKC
RTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIV
NKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPK
ELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFI
DSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRT
DFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEG
LFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGI
FMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSY
KMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYA
RAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPAL
YVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTT
KPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQ
IIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLY
DDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVE
VQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQLT
ATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKET
GYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLP
GQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTP
GSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWN
YNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEGEVYSADREDLYA
NT seq
7008 nt
NT seq
+upstream
nt +downstream
nt
atggccggagtgtttccttatcgagggccgggtaacccggtgcctggccctctagccccg
ctaccggactacatgtcggaggagaagctgcaggagaaagctcgaaaatggcagcaattg
caggccaagcgctatgcagaaaagcggaagtttgggtttgtggatgcccagaaggaagac
atgcccccagaacatgtcaggaagatcattcgagaccatggagacatgaccaacaggaag
ttccgccatgacaaaagggtttacttgggtgccctaaagtacatgccccacgcagtcctc
aaactcctggagaacatgcctatgccttgggagcagattcgggatgtgcctgtgctgtac
cacatcactggagccatttccttcgtcaatgagattccctgggtcattgaacctgtctac
atctcccagtgggggtcaatgtggattatgatgcgccgagaaaaaagagataggaggcat
ttcaagaggatgcgttttcccccttttgatgatgaggagccgcccttggactatgctgac
aacatcctagatgttgagccactggaggccattcagctagagctggaccctgaggaggac
gcccctgtgttggactggttctatgaccaccagccgttgagggacagcaggaagtatgta
aatggctccacttaccagcgctggcagttcacactacctatgatgtcgactctctaccgc
ctggctaatcagctcctgacagacttggtggatgacaactacttctacctgtttgatttg
aaggccttctttacgtccaaggcactcaatatggccattcctggaggccccaaatttgaa
cctcttgttcgagacatcaacctacaggatgaagactggaatgaattcaatgatattaac
aagattatcatccggcagcctatccgcactgagtacaagattgcttttccttacttgtac
aacaatcttccacaccatgtccacctcacctggtaccatactcccaatgttgtattcatc
aaaactgaggatcctgacttgccagctttctactttgaccctttgatcaacccaatctcc
cataggcactcagtcaagagccaggaaccattgccggatgatgatgaggaatttgagctc
ccggagtttgtggagcccttcctgaaggacacacccctctatacagacaatacagccaat
ggcattgccctgctctgggccccgcggcccttcaacctacgctctggtcgcacccgtcgg
gccctggacataccccttgtcaagaactggtatcgggagcattgtcctgccgggcagcct
gtgaaagtgagggtctcctaccagaagctgcttaagtactatgtgctgaatgccctgaag
catcggccccctaaggctcaaaagaagaggtatttgttccgctccttcaaagccaccaaa
ttctttcagtccacaaagctggactgggtggaggttgggctccaggtttgccgccagggc
tacaacatgctcaaccttctcattcaccgcaaaaacctcaactacctgcacctggactac
aacttcaacctcaagcctgtgaaaacgctcaccaccaaggaaagaaagaaatctcgtttt
gggaatgctttccacctgtgtcgggaagttctgcgtttgactaagctggtggtggatagt
cacgtgcagtatcggctgggcaatgtggatgccttccagctggcagatggattgcagtat
atatttgcccatgttgggcagttgacgggcatgtatcgatacaaatacaagctgatgcga
cagattcgcatgtgcaaggacctgaagcatctcatctattatcgtttcaacacgggccct
gtagggaagggtcctggctgtggcttctgggctgccggttggcgagtctggctctttttc
atgcgtggcattacccctttattagagcgatggcttggcaacctcctggcccggcagttt
gaaggtcgacactcaaagggggtggcaaagacagtaacaaagcagcgagtggagtcacat
tttgaccttgagctgcgggcagctgtgatgcatgatattctggacatgatgcctgagggg
atcaagcagaacaaggcccggacaatcctgcagcacctcagtgaagcctggcgctgctgg
aaagccaacattccctggaaggtccctgggctgccgacgcccatagagaatatgatcctt
cgatacgtgaaggccaaggctgactggtggaccaacactgcccactacaaccgagaacgg
atccgccgaggggccactgtggacaagactgtttgtaaaaagaatctgggccgcctcacc
cggctctatctgaaggcagaacaggagcggcagcacaactacctgaaggacgggccttac
atcacagcggaggaagcagtggcagtatataccaccacagtgcattggttggaaagccgc
aggttttcacccatcccattccccccactctcctataagcatgacaccaagttgctcatc
ttggcattggagcggctcaaggaagcttatagtgtgaagtctcggttgaaccagtctcag
agggaggagctaggtctgatcgagcaggcctacgataacccccacgaggcgctgtcccgc
atcaagcgtcacctcctcacacagagagccttcaaagaggtgggcattgagttcatggat
ctgtatagccacctcgttccagtatatgatgttgagcccctggagaagataactgatgct
tacctggaccagtacctgtggtatgaagccgacaagcgccgcctgttcccaccctggatt
aagcctgcagacacagaaccacctccgctgcttgtttacaagtggtgtcaaggcatcaat
aacctgcaggacgtgtgggagacgagtgaaggcgagtgcaatgtcatgctggaatcccgc
tttgagaagatgtatgagaagatcgacttgactctgctcaacaggctgctgcgcctcatc
gtggaccacaacatagccgactacatgacagccaagaacaacgtcgtcatcaactataag
gacatgaaccatacgaattcatatgggatcatcagaggcctgcagtttgcctcattcatc
gtgcagtattatggcctggtgatggatttgcttgtattgggattgcaccgggccagtgag
atggctgggccccctcagatgccaaatgactttctcagtttccaggacatagccactgag
gctgcccaccccatccgtctcttctgcagatacattgatcgcatccatatttttttcagg
ttcacagcagatgaggctcgggacctgattcaacgttacctgacagagcaccctgacccc
aataatgaaaacatcgttggctataataacaagaagtgctggccccgagatgcccgcatg
cgcctcatgaaacatgatgttaacttaggccgggcggtattctgggacatcaagaaccgc
ttgccacggtcagtgactacagttcagtgggagaacagcttcgtgtctgtgtacagtaag
gacaaccccaacctgctgttcaacatgtgtggcttcgagtgccgcatcctgcctaagtgc
cgcaccagctatgaggagttcacccacaaggacggggtctggaacctgcagaatgaggtt
actaaggagcgcacagctcagtgtttcctgcgtgtggacgatgagtcaatgcagcgcttc
cacaaccgcgtgcgtcagattctcatggcctctgggtccaccaccttcaccaagattgtg
aataagtggaatacagctctcattggccttatgacatactttcgggaggctgtggtgaac
acccaagagctcttggacttactggtgaagtgtgagaacaaaatccagacacgtatcaag
attggactcaactccaagatgccaagtcggttccccccggttgtgttctacacccctaag
gagttgggtggactcggcatgctctcaatgggccatgtgctcatcccccaatccgacctc
aggtggtccaaacagacagatgtaggtatcacacactttcgttcaggaatgagccatgaa
gaagaccagctcattcccaacttgtaccgctacatacagccatgggagagcgagttcatt
gattctcagcgggtctgggctgagtacgcactcaagaggcaagaggccattgctcagaac
agacgcctgactttagaagacctagaagattcatgggatcgtggcattcctcgaatcaat
accctcttccagaaggaccggcacacactggcttatgataagggctggcgtgtcagaact
gactttaagcagtatcaggttttgaagcagaatccgttctggtggacacaccagcggcat
gatgggaagctctggaacctgaacaactaccgtacagacatgatccaggccctgggcggt
gtggaaggcattctggaacacacactctttaagggcacttacttccctacctgggagggg
cttttctgggagaaggccagtggctttgaggaatctatgaagtggaagaagctaactaat
gctcagcgatcaggactgaaccagattcccaatcgtagattcaccctctggtggtccccg
accattaatcgagccaatgtatatgtaggctttcaggtgcagctagacctgacgggtatc
ttcatgcacggcaagatccccacgctgaagatctctctcatccagatcttccgagctcac
ttgtggcagaagatccatgagagcattgttatggacttatgtcaggtgtttgaccaggaa
cttgatgcactggaaattgagacagtacaaaaggagacaatccatccccgaaagtcatat
aagatgaactcttcctgtgcagatatcctgctctttgcctcctataagtggaatgtctcc
cggccctcattgctggctgactccaaggatgtgatggacagcaccaccacccagaaatac
tggattgacatccagttgcgctggggggactatgattcccacgacattgagcgctacgcc
cgggccaagttcctggactacaccaccgacaacatgagtatctacccttcgcccacaggt
gtactcatcgccattgacctggcctataacttgcacagtgcctatggaaactggttccca
ggcagcaagcctctcatacaacaggccatggccaagatcatgaaggcaaaccctgccctg
tatgtgttacgtgaacggatccgcaaggggctacagctctattcatctgaacccactgag
ccttatttgtcttctcagaactatggtgagctcttctccaaccagattatctggtttgtg
gatgacaccaacgtctacagagtgactattcacaagacctttgaagggaacttgacaacc
aagcccatcaacggagccatcttcatcttcaacccacgcacagggcagctgttcctcaag
ataatccacacgtccgtgtgggcgggacagaagcgtttggggcagttggctaagtggaag
acagctgaggaggtggccgccctgatccgatctctgcctgtggaggagcagcccaagcag
atcattgtcaccaggaagggcatgctggacccactggaggtgcacttactggacttcccc
aatattgtcatcaaaggatcggagctccaactccctttccaggcgtgtctcaaggtggaa
aaattcggggatctcatccttaaagccactgagccccagatggttctcttcaacctctat
gacgactggctcaagactatttcatcttacacggccttctcccgtctcatcctgattctg
cgtgccctacatgtgaacaacgatcgggcaaaagtgatcctgaagccagacaagactact
attacagaaccacaccacatctggcccactctgactgacgaagaatggatcaaggtcgag
gtgcagctcaaggatctgatcttggctgactacggcaagaaaaacaatgtgaacgtggca
tcactgacacaatcagaaattcgagacatcatcctgggtatggagatctcggcaccgtca
cagcagcggcagcagatcgctgagatcgagaagcagaccaaggaacaatcgcagctgacg
gcaacacagactcgcactgtcaacaagcatggcgatgagatcatcacctccaccaccagc
aactatgagacccagactttctcatccaagactgagtggagggtcagggccatctctgct
gccaacctgcacctaaggaccaatcacatctatgtttcatctgacgacatcaaggagact
ggctacacctacatccttcccaagaatgtgcttaagaagttcatctgcatatctgacctt
cgggcccaaattgcaggatacctatatggggtgagcccaccagataacccccaggtgaag
gagatccgctgcattgtgatggtgccgcagtggggcactcaccagaccgtgcacctgcct
ggccagctgccccagcatgagtacctcaaggagatggaacccttaggttggatccacact
cagcccaatgagtccccgcagttatcaccccaggatgtcaccacccatgccaagatcatg
gctgacaacccatcttgggatggcgagaagaccattatcatcacatgcagcttcacgcca
ggctcctgtacactgacggcctacaagctgacccccagtggctacgaatggggccgccag
aacacagacaagggcaacaaccccaagggctacctgccttcacactatgagagggtgcag
atgctgctgtcggaccgtttccttggcttcttcatggtccctgcccagtcctcgtggaac
tacaacttcatgggtgttcggcatgaccccaacatgaaatatgagctacagctggcgaac
cccaaagagttctaccacgaggtgcacaggccctctcacttcctcaactttgctctcctg
caggagggggaggtttactctgcggatcgggaggacctgtatgcctga
DBGET
integrated database retrieval system
